Chiral pharmacokinetics of tetramisole stereoisomers - enantioselective quantification of levamisole and dexamisole in serum samples from users of adulterated cocaine.
Sign Up to like & getrecommendations! Published in 2022 at "Drug testing and analysis"
DOI: 10.1002/dta.3227
Abstract: Phenyltetrahydroimidazothiazole (PTHIT, tetramisole) ist the most frequently used adulterant of cocaine and exists in the two enantiomeric forms levamsiole (S) and dexamisole (R). Existing studies show diverse fractions of samples containing enantiopure levamsiole, levamisole-enriched mixtures… read more here.
Keywords: chiral pharmacokinetics; pthit; serum samples; positive samples ... See more keywords
DNRLCNN: A CNN Framework for Identifying MiRNA-Disease Associations Using Latent Feature Matrix Extraction with Positive Samples.
Sign Up to like & getrecommendations! Published in 2022 at "Interdisciplinary sciences, computational life sciences"
DOI: 10.1007/s12539-022-00509-z
Abstract: Emerging evidence indicates that miRNAs have strong relationships with many human diseases. Investigating the associations will contribute to elucidating the activities of miRNAs and pathogenesis mechanisms, and providing new opportunities for disease diagnosis and drug… read more here.
Keywords: positive samples; latent feature; mirna disease; feature ... See more keywords
Salmonella on Australian cage egg farms: Observations from hatching to end of lay.
Sign Up to like & getrecommendations! Published in 2020 at "Food microbiology"
DOI: 10.1016/j.fm.2019.103384
Abstract: Single-aged caged layer hen flocks were monitored for Salmonella over the course of their lifetime. Chicks from both flocks were Salmonella negative at hatch and remained negative during rearing. Pullets were transported to production farms… read more here.
Keywords: salmonella positive; salmonella; australian cage; egg ... See more keywords
A simple and rapid approach to prepare Sindbis and West Nile viral RNA controls for differentiation between positive samples and laboratory contamination.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of virological methods"
DOI: 10.1016/j.jviromet.2020.113822
Abstract: Reverse transcription-polymerase chain reaction (RT-PCR) is frequently used for surveillance and diagnosis of arboviruses and emerging viruses. A disadvantage of RT-PCR assays, especially nested assays, is the potential for false-positive results caused by laboratory contamination… read more here.
Keywords: positive control; positive samples; contamination; laboratory contamination ... See more keywords
Detection and genotypes of Toxoplasma gondii DNA in feces of domestic cats in Colombia
Sign Up to like & getrecommendations! Published in 2020 at "Parasite"
DOI: 10.1051/parasite/2020023
Abstract: The high prevalence of Toxoplasma gondii in the human population in Colombia has been linked to the existence of a high density of urban stray cats, exposing the whole population to a high density of… read more here.
Keywords: fecal samples; dna; microscopy; pcr ... See more keywords
Detection of bovine pestiviruses in sera of beef calves by a RT-PCR based on a newly designed set of pan–bovine pestivirus primers
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Veterinary Diagnostic Investigation"
DOI: 10.1177/1040638719826299
Abstract: The pestiviruses bovine viral diarrhea virus 1 and 2 (BVDV-1 and -2, respectively) and HoBi-like pestivirus (HoBiPeV) are important pathogens of cattle, and a number of reverse-transcription PCR (RT-PCR)–based assays have been developed for their… read more here.
Keywords: pestivirus; bovine; positive samples; pestivirus primers ... See more keywords
How to balance the bioinformatics data: pseudo-negative sampling
Sign Up to like & getrecommendations! Published in 2019 at "BMC Bioinformatics"
DOI: 10.1186/s12859-019-3269-4
Abstract: Imbalanced datasets are commonly encountered in bioinformatics classification problems, that is, the number of negative samples is much larger than that of positive samples. Particularly, the data imbalance phenomena will make us underestimate the performance… read more here.
Keywords: positive samples; pseudo negative; negative sampling; negative samples ... See more keywords
Detection of ALV p27 in cloacal swabs and virus isolation medium by sELISA
Sign Up to like & getrecommendations! Published in 2019 at "BMC Veterinary Research"
DOI: 10.1186/s12917-019-2150-z
Abstract: BackgroundAvian leukosis (AL), which is caused by avian leukosis virus (ALV), has led to substantial economic losses in the poultry industry. The kit used to detect all ALV-positive chickens in breeder flocks is very important… read more here.
Keywords: cloacal swabs; swabs virus; positive samples; virus isolation ... See more keywords
A simple method for the preparation of positive samples to preliminarily determine the quality of phosphorylation-specific antibody
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DOI: 10.1371/journal.pone.0272138
Abstract: Protein phosphorylation is one of the most common and important post-translational modifications and is involved in many biological processes, including DNA damage repair, transcriptional regulation, signal transduction, and apoptosis regulation. The use of antibodies targeting… read more here.
Keywords: phosphorylation specific; positive samples; quality phosphorylation; method ... See more keywords
Mycobiome Sequencing and Analysis Applied to Fungal Community Profiling of the Lower Respiratory Tract During Fungal Pathogenesis
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2019.00512
Abstract: Invasive fungal infections are an increasingly important cause of human morbidity and mortality. We generated a next-generation sequencing (NGS)-based method designed to detect a wide range of fungi and applied it to analysis of the… read more here.
Keywords: analysis; culture positive; culture negative; positive samples ... See more keywords
Tertiary Lymphoid Structures and Chemokine Landscape in Virus-Positive and Virus-Negative Merkel Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.811586
Abstract: Tertiary lymphoid structures (TLSs) are used as biomarkers in many cancers for predicting the prognosis and assessing the response to immunotherapy. In Merkel cell carcinoma (MCC), TLSs have only been examined in MCPyV-positive cases. Here,… read more here.
Keywords: prognosis; mcpyv; mcpyv positive; mcpyv negative ... See more keywords