Prognostic value of PD-L1 combined positive score in patients with upper tract urothelial carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-021-02890-y
Abstract: Upper tract urothelial carcinoma (UTUC) is relatively rare in Western countries. The impact of programmed death-ligand 1 (PD-L1) expression on UTUC remains unclear because previous studies have focused on bladder UC. We investigated the association… read more here.
Keywords: upper tract; tract urothelial; positive score; urothelial carcinoma ... See more keywords
An artificial intelligence‐powered PD‐L1 combined positive score (CPS) analyser in urothelial carcinoma alleviating interobserver and intersite variability
Sign Up to like & getrecommendations! Published in 2024 at "Histopathology"
DOI: 10.1111/his.15176
Abstract: Immune checkpoint inhibitors targeting programmed death‐ligand 1 (PD‐L1) have shown promising clinical outcomes in urothelial carcinoma (UC). The combined positive score (CPS) quantifies PD‐L1 22C3 expression in UC, but it can vary between pathologists due… read more here.
Keywords: score cps; urothelial carcinoma; positive score; combined positive ... See more keywords
Abstract 749: Pathology training for combined positive score algorithm for the assessment of PD-L1 in human cancer tissues
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Trials"
DOI: 10.1158/1538-7445.am2020-749
Abstract: Introduction: A pathologist training and testing procedure was developed for evaluating PD-L1 expression using the Combined Positive Score (CPS) algorithm, with effectiveness assessed by examining the results of scoring reproducibility studies. Background: The CPS algorithm… read more here.
Keywords: pathology; positive score; cps algorithm; cancer ... See more keywords
Development of the combined positive score (CPS) for the evaluation of PD-L1 in solid tumors with the immunohistochemistry assay PD-L1 IHC 22C3 pharmDx.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.e14589
Abstract: e14589Background: Developing clinically relevant and highly reproducible scoring methods for PD-L1 to identify patients who will respond effectively to anti-PD-1 therapy is key in the development o... read more here.
Keywords: positive score; development combined; combined positive; development ... See more keywords
Combined Positive Score for Programmed Death Ligand-1 Expression and Inflammatory Microenvironment in Gastrointestinal Stromal Tumors
Sign Up to like & getrecommendations! Published in 2022 at "Medicina"
DOI: 10.3390/medicina58020174
Abstract: Background and Objectives: GISTs are the most frequent type of mesenchymal neoplasm of the digestive tract. The prognosis is mainly determined by tumor dimensions, mitotic rate and location, but other less well-documented factors can influence… read more here.
Keywords: expression; type; immune cells; positive score ... See more keywords