Positive selection of IL‐33 in adaptive immunity of domestic Chinese goats
Sign Up to like & getrecommendations! Published in 2017 at "Ecology and Evolution"
DOI: 10.1002/ece3.2813
Abstract: Abstract The identification of the candidate genes that play key role in phenotypic variation in livestock populations can provide new information about evolution and positive selection. IL‐33 (71954) (Interleukin) gene is associated with the increased… read more here.
Keywords: positive selection; selection; selection adaptive; adaptive immunity ... See more keywords
Evolutionary conservation and positive selection of influenza A nucleoprotein CTL epitopes for universal vaccination
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27662
Abstract: Influenza (flu) infection is a leading cause of respiratory diseases and death worldwide. Although seasonal flu vaccines are effective at reducing morbidity and mortality, such effects rely on the odds of successful prediction of the… read more here.
Keywords: evolutionary conservation; vaccination; positive selection; influenza ... See more keywords
Insights into Dietary Switch in Cetaceans: Evidence from Molecular Evolution of Proteinases and Lipases
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Evolution"
DOI: 10.1007/s00239-020-09952-2
Abstract: Fossil evidence suggests that cetaceans evolved from artiodactylans. Thus, there was a major dietary change from herbivorous to carnivorous during their transition from a terrestrial to an aquatic environment. However, the molecular evolutionary mechanisms underlying… read more here.
Keywords: molecular evolution; positive selection; proteinases lipases; evidence ... See more keywords
A Re-Assessment of Positive Selection on Mitochondrial Genomes of High-Elevation Phrynocephalus Lizards
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Evolution"
DOI: 10.1007/s00239-020-09991-9
Abstract: Due to their integral roles in oxidative phosphorylation, mitochondrially encoded proteins represent common targets of selection in response to altitudinal hypoxia across high-altitude taxa. While previous studies revealed evidence of positive selection on mitochondrial genomes… read more here.
Keywords: positive selection; selection; mitochondrial genomes; high altitude ... See more keywords
One-third of the plastid genes evolved under positive selection in PACMAD grasses
Sign Up to like & getrecommendations! Published in 2017 at "Planta"
DOI: 10.1007/s00425-017-2781-x
Abstract: AbstractMain conclusionWe demonstrate thatrbcLunderwent strong positive selection during the C3–C4photosynthetic transitions in PACMAD grasses, in particular the 3′ end of the gene. In contrast, selective pressures on other plastid genes vary widely and environmental drivers… read more here.
Keywords: pacmad grasses; positive selection; genes evolved; selection ... See more keywords
A MicroRNA Linking Human Positive Selection and Metabolic Disorders
Sign Up to like & getrecommendations! Published in 2020 at "Cell"
DOI: 10.1016/j.cell.2020.09.017
Abstract: Positive selection in Europeans at the 2q21.3 locus harboring the lactase gene has been attributed to selection for the ability of adults to digest milk to survive famine in ancient times. However, the 2q21.3 locus… read more here.
Keywords: positive selection; selection; mir 128; metabolic ... See more keywords
Complete genome analysis identifies recombinant events and positive selection sites of hepatitis C virus from mainland China during 2010-2019.
Sign Up to like & getrecommendations! Published in 2021 at "Virus research"
DOI: 10.1016/j.virusres.2021.198354
Abstract: Identification of new recombinant HCV strains and positive selection sites are crucially important for the formulation of virus intervention measures. However, little is known about the recombinant variant information and positive selection sites of circulating… read more here.
Keywords: mainland china; positive selection; selection; china 2010 ... See more keywords
Repurposing the Homing Endonuclease I-SceI for Positive Selection and Development of Gene-Editing Technologies.
Sign Up to like & getrecommendations! Published in 2022 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.1c00340
Abstract: Prokaryote genomes encode diverse programmable DNA endonucleases with significant potential for biotechnology and gene editing. However, these endonucleases differ significantly in their properties, which must be screened and measured. While positive selection screens based on… read more here.
Keywords: homing endonuclease; endonuclease scei; gene editing; positive selection ... See more keywords
Genome-wide estimation of recombination, mutation and positive selection enlightens diversification drivers of Mycobacterium bovis
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DOI: 10.1038/s41598-021-98226-y
Abstract: Genome sequencing has reinvigorated the infectious disease research field, shedding light on disease epidemiology, pathogenesis, host–pathogen interactions and also evolutionary processes exerted upon pathogens. Mycobacterium tuberculosis complex (MTBC), enclosing M. bovis as one of its… read more here.
Keywords: positive selection; diversification; bovis; recombination ... See more keywords
RNA structure-altering mutations underlying positive selection on Spike protein reveal novel putative signatures to trace crossing host-species barriers in Betacoronavirus
Sign Up to like & getrecommendations! Published in 2022 at "RNA Biology"
DOI: 10.1080/15476286.2022.2115750
Abstract: ABSTRACT Similar to other RNA viruses, the emergence of Betacoronavirus relies on cross-species viral transmission, which requires careful health surveillance monitoring of protein-coding information as well as genome-wide analysis. Although the evolutionary jump from natural… read more here.
Keywords: positive selection; rna; biology; sars cov ... See more keywords
Detecting signals of adaptive evolution in grape plastomes with a focus on the Cretaceous-Paleogene (K/Pg) transition.
Sign Up to like & getrecommendations! Published in 2022 at "Annals of botany"
DOI: 10.1093/aob/mcac128
Abstract: BACKGROUND AND AIMS Although the plastid genes are being largely used in phylogenetic studies, signals of positive selection have been scarcely investigated in grape family. The plastomes from 91 accessions of Vitaceae were examined to… read more here.
Keywords: plastid genes; positive selection; cretaceous paleogene; paleogene transition ... See more keywords