Transcriptome profile and unique genetic evolution of positively selected genes in yak lungs
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DOI: 10.1007/s10709-017-0005-8
Abstract: The yak (Bos grunniens), which is a unique bovine breed that is distributed mainly in the Qinghai-Tibetan Plateau, is considered a good model for studying plateau adaptability in mammals. The lungs are important functional organs… read more here.
Keywords: genes yak; selected genes; yak lungs; positively selected ... See more keywords
Positive Selection at Key Residues in the HIV Envelope Distinguishes Broad and Strain-Specific Plasma Neutralizing Antibodies
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Virology"
DOI: 10.1128/jvi.01685-18
Abstract: Millions of people are still being infected with HIV decades after the first recognition of the virus. Currently, no vaccine is able to elicit bNAbs that will prevent infection by global HIV strains. Several studies… read more here.
Keywords: evolution; diversity; hiv; strain specific ... See more keywords
Response to: ‘Similarities and differences between severe COVID-19 pneumonia and anti-MDA-5 positive dermatomyositis associated rapidly progressive interstitial lung diseases: a challenge for the future’ by Wang et al
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DOI: 10.1136/annrheumdis-2020-218712
Abstract: The insulin/insulin-like signaling and target of rapamycin (IIS/TOR) network regulates lifespan and reproduction, as well as metabolic diseases, cancer, and aging. Despite its vital role in health, comparative analyses of IIS/TOR have been limited to… read more here.
Keywords: network; positively selected; receptor; iis tor ... See more keywords
Identification and Characterization of Positively Selected Mutations in Nef of Four HIV-1 Major Subtypes from Los Alamos National Laboratory.
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DOI: 10.2174/1570162x16666180330140807
Abstract: BACKGROUND Human immunodeficiency virus-1 (HIV-1) mutates rapidly to escape host immune pressure. This results in the generation of positively selected mutations (PSM) throughout the viral genome. Escape mutations in Nef, one of the accessory proteins… read more here.
Keywords: alamos national; selected mutations; hiv; positively selected ... See more keywords