Utilizing in silico and in vitro methods to identify possible binding sites of a novel ligand against Pseudomonas aeruginosa phospholipase toxin ExoU
Sign Up to like & getrecommendations! Published in 2022 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2021.101188
Abstract: Multi-drug resistant infections caused by the opportunistic pathogen, Pseudomonas aeruginosa (P. aeruginosa), are a continuing problem that contribute to morbidity and mortality in immunocompromised hosts such as cystic fibrosis (CF), wound and burn patients. The… read more here.
Keywords: toxin exou; possible binding; identify possible; novel ligand ... See more keywords
Possible binding sites and interactions of propanidid and AZD3043 within the γ-aminobutyric acid type A receptor (GABAAR)
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2017.1403959
Abstract: Propanidid is an intravenous anesthetic with transient action and rapid recovery features, but it is clinically unacceptable due to its side effects. AZD-3043, an analog of propanidid with the methoxy group substituted by the ethoxy… read more here.
Keywords: propanidid azd; acid type; possible binding; azd 3043 ... See more keywords