The neuroprotective effect and possible therapeutic application of xenon in neurological diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of neuroscience research"
DOI: 10.1002/jnr.24958
Abstract: Xenon is an inert gas with stable chemical properties which is used as an anesthetic. Recent in vitro and in vivo findings indicate that xenon also elicits an excellent neuroprotective effect in subanesthetic concentrations. The… read more here.
Keywords: neuroprotective effect; xenon; neurological diseases; possible therapeutic ... See more keywords
Heritable Skeletal Disorders Arising from Defects in Processing and Transport of Type I Procollagen from the ER: Perspectives on Possible Therapeutic Approaches.
Sign Up to like & getrecommendations! Published in 2018 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2017_67
Abstract: Rare bone disorders are a heterogeneous group of diseases, initially associated with mutations in type I procollagen (PC) genes. Recent developments from dissection at the molecular and cellular level have expanded the list of disease-causing… read more here.
Keywords: transport; possible therapeutic; type procollagen; skeletal disorders ... See more keywords
Possible therapeutic targets and promising drugs based on unsymmetrical hetaryl-substituted porphyrins to combat SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Pharmaceutical Analysis"
DOI: 10.1016/j.jpha.2021.08.003
Abstract: Coronavirus disease 2019 is a serious disease that causes acute respiratory syndrome and negatively affects the central nervous system. SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) crosses the blood-brain barrier due to the S protein… read more here.
Keywords: protein; substituted porphyrins; hetaryl substituted; possible therapeutic ... See more keywords
Ketamine for post-traumatic stress disorders and it's possible therapeutic mechanism
Sign Up to like & getrecommendations! Published in 2021 at "Neurochemistry International"
DOI: 10.1016/j.neuint.2021.105044
Abstract: Posttraumatic stress disorder (PTSD) is a devastating medical illness, for which currently available pharmacotherapies have poor efficacy. Accumulating evidence from clinical and preclinical animal investigations supports that ketamine exhibits a rapid and persistent effect against… read more here.
Keywords: mechanism; therapeutic mechanism; ketamine; mechanism ketamine ... See more keywords
An overview of the possible therapeutic role of SUMOylation in the treatment of Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2018 at "Pharmacological Research"
DOI: 10.1016/j.phrs.2017.12.023
Abstract: &NA; Nowadays, Alzheimer's disease (AD) is recognized as a multifactorial neurological pathology whose complexity is the cause of our still low achievements in the understanding of the associated mechanisms as well the discovery of a… read more here.
Keywords: sumoylation; alzheimer disease; pathology; possible therapeutic ... See more keywords
Remdesivir as a possible therapeutic option for the COVID-19
Sign Up to like & getrecommendations! Published in 2020 at "Travel Medicine and Infectious Disease"
DOI: 10.1016/j.tmaid.2020.101615
Abstract: This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive… read more here.
Keywords: version; remdesivir possible; option covid; therapeutic option ... See more keywords
Myokines as Possible Therapeutic Targets in Cancer Cachexia
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Immunology Research"
DOI: 10.1155/2018/8260742
Abstract: Cachexia is an extremely serious syndrome which occurs in most patients with different cancers, and it is characterized by systemic inflammation, a negative protein and energy balance, and involuntary loss of body mass. This syndrome… read more here.
Keywords: therapeutic targets; targets cancer; myokines possible; cancer cachexia ... See more keywords
Possible Therapeutic Potential of Cysteinyl Leukotriene Receptor Antagonist Montelukast in Treatment of SARS-CoV-2-Induced COVID-19
Sign Up to like & getrecommendations! Published in 2021 at "Pharmacology"
DOI: 10.1159/000518359
Abstract: Background: The coronavirus disease-19 (COVID-19) pandemic is a serious devastating disease and has posed a global health emergency. So far, there is not any specific therapy approved till date to control the clinical symptoms of… read more here.
Keywords: cysteinyl leukotriene; control; covid; possible therapeutic ... See more keywords
Possible therapeutic effect of magnesium in ocular diseases
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Basic and Clinical Physiology and Pharmacology"
DOI: 10.1515/jbcpp-2019-0107
Abstract: Abstract Magnesium (Mg2+) is one of the major elements required to maintain normal metabolism and ionic balances in ocular tissues. The physiological role of Mg2+ is mediated through maintaining the Na+-K+-ATPase on membrane, favoring energy-generating… read more here.
Keywords: therapeutic effect; effect magnesium; ocular diseases; mg2 ... See more keywords
Erucic Acid: A Possible Therapeutic Agent for Neurodegenerative Diseases.
Sign Up to like & getrecommendations! Published in 2023 at "Current molecular medicine"
DOI: 10.2174/1566524023666230509123536
Abstract: Neurodegenerative disorders are among the most common life-threatening disorders among the elderly worldwide and are marked by neuronal death in the brain and spinal cord. Several studies have demonstrated the beneficial role of dietary fatty… read more here.
Keywords: possible therapeutic; agent; erucic acid; acid ... See more keywords
Possible Therapeutic Effects of Ozone Mixture on Hypoxia in Tumor Development.
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DOI: 10.21873/anticanres.11334
Abstract: Recent literature highlights that ozone therapy could be considered a viable adjuvant therapy in oncological patients receiving radio-chemotherapy. The use of ozone therapy in these patients enhances the action of chemotherapy and at the same… read more here.
Keywords: ozone therapy; ozone mixture; effects ozone; therapeutic effects ... See more keywords