P0777 Sonographic transmural induction outcomes across advanced therapies in Crohn’s Disease
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjae190.0951
Abstract: Intestinal ultrasound (IUS) is increasingly being used to evaluate induction efficacy in both clinical practice and clinical trials. The differential healing rates across advanced therapies (AT) remains unknown. We aimed to quantify the rates of… read more here.
Keywords: disease; response; remission; across advanced ... See more keywords
Effect of pneumatic leg compression on post‐induction hypotension in elderly patients undergoing robot‐assisted laparoscopic prostatectomy: a double‐blind randomised controlled trial
Sign Up to like & getrecommendations! Published in 2023 at "Anaesthesia"
DOI: 10.1111/anae.15994
Abstract: Post‐induction hypotension is common and associated with postoperative complications. We hypothesised that pneumatic leg compression reduces post‐induction hypotension in elderly patients undergoing robot‐assisted laparoscopic prostatectomy. In this double‐blind randomised study, patients were allocated randomly to… read more here.
Keywords: leg; leg compression; post induction; pneumatic leg ... See more keywords
Association between preoperative autonomic nervous system function and post-induction hypotension in elderly patients: a protocol for a cohort study
Sign Up to like & getrecommendations! Published in 2023 at "BMJ Open"
DOI: 10.1136/bmjopen-2022-067400
Abstract: Introduction Post-induction hypotension (PIH), which is prevalent among elderly patients, is associated with adverse perioperative outcomes. As a critical part of blood pressure regulation, baroreflex control is believed to be closely related to intraoperative blood… read more here.
Keywords: induction hypotension; function; elderly patients; association preoperative ... See more keywords
Correlation between postprandial hypotension and post-induction hypotension in the elderly: a protocol for a prospective cohort study
Sign Up to like & getrecommendations! Published in 2025 at "BMJ Open"
DOI: 10.1136/bmjopen-2024-095466
Abstract: Introduction Post-induction hypotension (PIH) is particularly common in elderly patients undergoing general anaesthesia and is associated with severe postoperative complications. Autonomic nervous system (ANS) dysfunction is a potential risk factor for significant haemodynamic fluctuations during… read more here.
Keywords: hypotension; pih; study; post induction ... See more keywords
PTH-081 Ustekinumab treatment strategies in refractory Crohn’s Disease: Real-world effectiveness data from a UK IBD centre
Sign Up to like & getrecommendations! Published in 2019 at "Gut"
DOI: 10.1136/gutjnl-2019-bsgabstracts.140
Abstract: Introduction Ustekinumab (UST) is a human IgG1 kappa mAb to the shared p40 subunit of IL-12 and IL-23 which are involved in TH1 and TH17 mediated pathways of Crohn’s disease (CD) pathogenesis. NICE approved UST… read more here.
Keywords: effectiveness; year; post induction; response ... See more keywords
Lipidomic Analysis of Flt3-ITD AML Cells Treated with Intensive Chemotherapy and Independent of Concomitant Sorafenib Display a Profile of Increased Susceptibility to Ferroptosis
Sign Up to like & getrecommendations! Published in 2024 at "Blood"
DOI: 10.1182/blood-2024-207280
Abstract: Introduction The randomised trial of (pre-allogeneic transplant) 2:1 sorafenib to placebo plus intensive chemotherapy in Flt3-ITD AML (Blood, 2023 Dec 7) did not meet the primary end-point of improved event-free survival (EFS) after a median… read more here.
Keywords: diagnosis; aml; post; chemotherapy ... See more keywords
Consolidation (Cons) and maintenance (Maint) approaches in primary central nervous system lymphoma (PCNSL) after high-dose methotrexate induction in transplant-ineligible patients
Sign Up to like & getrecommendations! Published in 2025 at "Blood"
DOI: 10.1182/blood-2025-3671
Abstract: PCNSL is a rare, aggressive non-Hodgkin lymphoma that primarily affects older adults. Standard treatment involves high-dose methotrexate (HD-MTX)–based induction followed by Cons and/or Maint. Autologous stem cell transplant is preferred, but many are ineligible due… read more here.
Keywords: maint; cons maint; transplant ineligible; post induction ... See more keywords
Subclinical cardiac changes following CPX-351 induction in adults with favorable/intermediate-risk AML
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DOI: 10.1182/blood-2025-5239
Abstract: Background: CPX-351 is a liposomal formulation of daunorubicin and cytarabine, approved for the treatment of newly diagnosed therapy-related acute myeloid leukemia (AML) and AML with myelodysplasia-related changes in adults. Liposomal encapsulation markedly increases the plasma… read more here.
Keywords: cpx 351; risk; post induction; induction ... See more keywords
Outcomes in children with NCI standard-risk b-acute lymphoblastic leukemia treated with intensified post-induction therapy: Results from Children's Oncology Group studies AALL0932 and AALL1131
Sign Up to like & getrecommendations! Published in 2025 at "Blood"
DOI: 10.1182/blood-2025-757
Abstract: Introduction End of induction (EOI) positive minimal residual disease (MRD) and unfavorable sentinel genetic lesions predict poor outcomes for patients with B-cell acute lymphoblastic leukemia (B-ALL). We examined outcomes for patients with newly diagnosed NCI… read more here.
Keywords: therapy; risk; vhr patients; post induction ... See more keywords
Identification of risk factors for post-induction hypotension in patients receiving 5-aminolevulinic acid: a single-center retrospective study
Sign Up to like & getrecommendations! Published in 2020 at "JA Clinical Reports"
DOI: 10.1186/s40981-020-00340-9
Abstract: Background 5-Aminolevulinic acid (5-ALA) is useful as a photodynamic agent, but its use commonly leads to hypotension. Although avoiding a mean arterial pressure (MAP) < 60 mmHg is important, the incidence of MAP < 60 mmHg when… read more here.
Keywords: post induction; aminolevulinic acid; group; induction hypotension ... See more keywords
Profiling renal sodium transporters in mice with nephron Ift88 disruption: Association with sex, cysts, and blood pressure
Sign Up to like & getrecommendations! Published in 2022 at "Physiological Reports"
DOI: 10.14814/phy2.15206
Abstract: Loss of nephron primary cilia due to disruption of the Ift88 gene results in sex‐ and age‐specific phenotypes involving renal cystogenesis, blood pressure (BP) and urinary Na+ excretion. Previous studies demonstrated that male mice undergoing… read more here.
Keywords: post induction; disruption; months post; induction ... See more keywords