Associated virus-bacterial vaccine based on seasonal LAIV and S. pneumoniae chimeric peptide provide protection against post-influenza pneumococcal infection in mouse model
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DOI: 10.1080/21505594.2022.2049496
Abstract: ABSTRACT Severe influenza complications are often caused by Streptococcus pneumoniae infection, which presents the most common cause of community-acquired pneumonia. We evaluated in a mouse model an associated virus-bacterial vaccine based on seasonal live influenza… read more here.
Keywords: virus bacterial; associated virus; mouse model; post influenza ... See more keywords
Eicosanoid-Activated PPARα Inhibits NFκB-Dependent Bacterial Clearance During Post-Influenza Superinfection
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DOI: 10.3389/fcimb.2022.881462
Abstract: Secondary bacterial infection (superinfection) post influenza is a serious clinical complication often leading to pneumonia and death. Eicosanoids are bioactive lipid mediators that play critical roles in the induction and resolution of inflammation. CYP450 lipid… read more here.
Keywords: activated ppar; superinfection; ppar inhibits; eicosanoid activated ... See more keywords