Mitochondrial uncoupling prodrug improves tissue sparing, cognitive outcome, and mitochondrial bioenergetics after traumatic brain injury in male mice
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24271
Abstract: Traumatic brain injury (TBI) results in cognitive impairment, which can be long‐lasting after moderate to severe TBI. Currently, there are no FDA‐approved therapeutics to treat the devastating consequences of TBI and improve recovery. This study… read more here.
Keywords: mitochondrial bioenergetics; traumatic brain; cognitive outcome; post injury ... See more keywords
Acute Sport Concussion Assessment Optimization: A Prospective Assessment from the CARE Consortium
Sign Up to like & getrecommendations! Published in 2019 at "Sports Medicine"
DOI: 10.1007/s40279-019-01155-0
Abstract: BackgroundNumerous medical organizations recommend a multifaceted approach to the assessment of concussion occurring during sporting events. A number of tools are available to clinicians, with a wide breadth of sensitivity and specificity; however, little work… read more here.
Keywords: assessment; post injury; concussion; concussion assessment ... See more keywords
The Natural History of Sport-Related Concussion in Collegiate Athletes: Findings from the NCAA-DoD CARE Consortium
Sign Up to like & getrecommendations! Published in 2021 at "Sports Medicine"
DOI: 10.1007/s40279-021-01541-7
Abstract: Sport-related concussion is recognized as a significant injury with variable recovery rates. This study defined the acute natural history of sport concussion in male and female collegiate athletes participating in a broad array of sports.… read more here.
Keywords: concussion; sport; collegiate athletes; post injury ... See more keywords
Acute stress promotes post-injury brain regeneration in fish
Sign Up to like & getrecommendations! Published in 2017 at "Brain Research"
DOI: 10.1016/j.brainres.2017.09.009
Abstract: The central nervous system and the immune system, the two major players in homeostasis, operate in the ongoing bidirectional interaction. Stress is the third player that exerts strong effect on these two 'supersystems'; yet, its… read more here.
Keywords: injury brain; post injury; stress; regeneration ... See more keywords
Retrograde influences of SCG axotomy on uninjured preganglionic neurons
Sign Up to like & getrecommendations! Published in 2018 at "Brain Research"
DOI: 10.1016/j.brainres.2018.04.014
Abstract: There is evidence that neuronal injury can affect uninjured neurons in the same neural circuit. The overall goal of this study was to understand the effects of peripheral nerve injury on uninjured neurons located in… read more here.
Keywords: preganglionic neurons; uninjured preganglionic; uninjured neurons; scg ... See more keywords
Newly synthesized phenanthroimidazole derivatives L082 as a safe anti-tumor and anti-injury inflammation bifunctional compound.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.173571
Abstract: Chemotherapy drugs exerts beneficial antitumor activity before and after cancer surgery. Post-injury complications are a potential hazard after surgical tumor resection. Inflammation caused by surgical stress is known to promote the progression of post-injury complications.… read more here.
Keywords: inflammation; post injury; injury; phenanthroimidazole derivatives ... See more keywords
Long-term increase in sensitivity to ketamine's behavioral effects in mice exposed to mild blast induced traumatic brain injury
Sign Up to like & getrecommendations! Published in 2022 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2021.113963
Abstract: Neurobehavioral deficits emerge in nearly 50% of patients following a mild traumatic brain injury (TBI) and may persist for months. Ketamine is used frequently as an anesthetic, analgesic and for management of persistent psychiatric complications.… read more here.
Keywords: day post; injury; ketamine; day ... See more keywords
Post-injury immunosuppression and secondary infections are caused by an AIM2 inflammasome-driven signaling cascade.
Sign Up to like & getrecommendations! Published in 2021 at "Immunity"
DOI: 10.1016/j.immuni.2021.02.004
Abstract: Loss of lymphocytes, particularly T cell apoptosis, is a central pathological event after severe tissue injury that is associated with increased susceptibility for life-threatening infections. The precise immunological mechanisms leading to T cell death after acute injury… read more here.
Keywords: aim2 inflammasome; cell; cell death; post injury ... See more keywords
Use of the King-Devick test for the identification of concussion in an amateur domestic women's rugby union team over two competition seasons in New Zealand
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2020.117162
Abstract: OBJECTIVE To investigate the use of the King-Devick (K-D) test for sideline assessment of concussive injuries in a New Zealand amateur women's rugby union team. DESIGN Prospective cohort observational. METHODS All players were K-D tested… read more here.
Keywords: concussion; injury concussion; test; assessment ... See more keywords
How do professional Australian Football League (AFL) players utilise social media during periods of injury? A mixed methods analysis.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of science and medicine in sport"
DOI: 10.1016/j.jsams.2017.10.034
Abstract: OBJECTIVES The objective of this study was to explore how social media is used by a population of injured professional athletes, by comparing the content and frequency of posts on social media, pre and post-injury.… read more here.
Keywords: social media; mixed methods; frequency; post injury ... See more keywords
Tau overexpression exacerbates neuropathology after repeated mild head impacts in male mice
Sign Up to like & getrecommendations! Published in 2020 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2019.104683
Abstract: Repeated mild traumatic brain injury (rmTBI) can lead to development of chronic traumatic encephalopathy (CTE), which is characterized by progressive neurodegeneration with presence of white matter damage, gliosis and hyper-phosphorylated tau. While animal models of… read more here.
Keywords: cell; repeated mild; mice; post injury ... See more keywords