Assessing long-term neuroinflammatory responses to encephalopathy using MRI approaches in a rat endotoxemia model
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DOI: 10.1007/s11357-018-0009-z
Abstract: Sepsis-associated encephalopathy (SAE) induces neuroinflammation, which is associated with cognitive impairment (CI). CI is also correlated with aging. We used contrast-enhanced magnetic resonance imaging (MRI), perfusion MRI, and MR spectroscopy to assess long-term alterations in… read more here.
Keywords: post lps; long term; model; mri ... See more keywords
Anti-inflammatory agent, OKN-007, reverses long-term neuroinflammatory responses in a rat encephalopathy model as assessed by multi-parametric MRI: implications for aging-associated neuroinflammation
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DOI: 10.1007/s11357-019-00094-y
Abstract: Lipopolysaccharide (LPS)–induced encephalopathy induces neuroinflammation. Long-term neuroinflammation is associated with aging and subsequent cognitive impairment (CI). We treated rats that had LPS-induced neuroinflammation with OKN-007, with an anti-inflammatory agent currently considered an anti-cancer investigational new… read more here.
Keywords: post lps; lps induced; long term; neuroinflammation ... See more keywords
Lipopolysaccharide (LPS) induced inflammatory changes to differentially expressed miRNAs of the host inflammatory response.
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DOI: 10.1016/j.vetimm.2021.110267
Abstract: In veterinary medicine, inflammation in swine is evaluated principally by clinical signs. This method is often unreliable when assessing large animal populations because of inconsistent interpretations of clinical observations. This study examined whether changes in… read more here.
Keywords: post lps; lps; inflammatory response; lipopolysaccharide lps ... See more keywords