Early increase in cortical T2 relaxation is a prognostic biomarker for the evolution of severe cortical damage, but not for epileptogenesis, after experimental traumatic brain injury.
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DOI: 10.1089/neu.2019.6796
Abstract: Prognostic biomarkers for post-injury outcome are necessary for the development of neuroprotective and antiepileptogenic treatments for traumatic brain injury (TBI). We hypothesized that T2 relaxation MRI predicts the progression of perilesional cortical pathology and epileptogenesis.… read more here.
Keywords: relaxation; epileptogenesis; pathology; post tbi ... See more keywords
Continuous remote ischemic conditioning attenuates cognitive and motor deficits from moderate traumatic brain injury
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DOI: 10.1097/ta.0000000000001835
Abstract: BACKGROUND While studies show that single-dose remote ischemic conditioning (RIC) improves outcomes, the effect of continuous (daily) RIC is unknown. Thus, we aimed to investigate the role of continuous RIC on cognitive and motor function… read more here.
Keywords: ischemic conditioning; remote ischemic; post tbi; tbi ... See more keywords
AMN Congress 2022 – Report of the panel on the effective treatment solutions for post-TBI cognitive problems
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medicine and Life"
DOI: 10.25122/jml-2022-1012
Abstract: © 2022 JOURNAL of MEDICINE and LIFE. VOL: 15 ISSUE: 7 JULY 2022 "The incidence of post – TBI cognitive problems is known – what should be done to offer effective treatment solutions?" – this… read more here.
Keywords: post tbi; medicine; effective treatment; treatment solutions ... See more keywords
Blood Glutamate Scavenging With Pyruvate as a Novel Preventative and Therapeutic Approach for Depressive-Like Behavior Following Traumatic Brain Injury in a Rat Model
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.832478
Abstract: Depression is a common and serious complication following traumatic brain injury (TBI). Both depression and TBI have independently been associated with pathologically elevated extracellular brain glutamate levels. In the setting of TBI, blood glutamate scavenging… read more here.
Keywords: pyruvate; glutamate; glutamate levels; brain ... See more keywords
Gut Microbiota Dysbiosis after Traumatic Brain Injury Contributes to Persistent Microglial Activation Associated with Upregulated Lyz2 and Shifted Tryptophan Metabolic Phenotype
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DOI: 10.3390/nu14173467
Abstract: Traumatic brain injury (TBI) is a common cause of disability and mortality, affecting millions of people every year. The neuroinflammation and immune response post-TBI initially have neuroprotective and reparative effects, but prolonged neuroinflammation leads to… read more here.
Keywords: microglial activation; post tbi; activation; gut microbiota ... See more keywords