Regulation of Rab5 isoforms by transcriptional and post‐transcriptional mechanisms in yeast
Sign Up to like & getrecommendations! Published in 2017 at "Febs Letters"
DOI: 10.1002/1873-3468.12785
Abstract: Rab5 GTPases are master regulators of early endosome biogenesis and transport. The genome of Saccharomyces cerevisiae encodes three Rab5 proteins: Vps21, the major isoform, Ypt52 and Ypt53. Here, we show that Vps21 is the most… read more here.
Keywords: rab5; transcriptional mechanisms; post transcriptional; ypt53 ... See more keywords
An update on post‐transcriptional regulation of retrotransposons
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14551
Abstract: Retrotransposons, including LINE‐1, Alu, SVA, and endogenous retroviruses, are one of the major constituents of human genomic repetitive sequences. Through the process of retrotransposition, some of them occasionally insert into new genomic locations by a… read more here.
Keywords: update post; rna; regulation; post transcriptional ... See more keywords
Non‐coding RNA regulatory networks in post‐transcriptional regulation of VEGFA in cancer
Sign Up to like & getrecommendations! Published in 2022 at "Iubmb Life"
DOI: 10.1002/iub.2620
Abstract: The switch from the normal quiescent vasculature to angiogenesis in tumors is induced by a variety of growth factors, released from cancer and stromal cells upon oxygen and nutrients deprivation. Vascular endothelial growth factor A… read more here.
Keywords: expression; transcriptional regulation; post transcriptional; cancer ... See more keywords
RNA mimicry in post‐transcriptional regulation by aminoacyl tRNA synthetases
Sign Up to like & getrecommendations! Published in 2019 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1564
Abstract: Aminoacyl tRNA synthetases (aaRS) are well studied for their roles in tRNA charging with cognate amino acid. Nevertheless, numerous lines of evidence indicate that these proteins have roles other than tRNA charging. These include coordination… read more here.
Keywords: transcriptional regulation; post transcriptional; trna synthetases; aminoacyl trna ... See more keywords
Post‐transcriptional regulation of polycistronic microRNAs
Sign Up to like & getrecommendations! Published in 2022 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1749
Abstract: An important proportion of microRNA (miRNA) genes tend to lie close to each other within animal genomes. Such genomic organization is generally referred to as miRNA clusters. Even though many miRNA clusters have been greatly… read more here.
Keywords: regulation polycistronic; mirna clusters; transcriptional regulation; post transcriptional ... See more keywords
Transcriptional and Post-transcriptional Regulatory Mechanisms Controlling Type III Secretion.
Sign Up to like & getrecommendations! Published in 2019 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2019_168
Abstract: Type III secretion systems (T3SSs) are utilized by numerous Gram-negative bacteria to efficiently interact with host cells and manipulate their function. Appropriate expression of type III secretion genes is achieved through the integration of multiple… read more here.
Keywords: secretion; iii secretion; post transcriptional; transcriptional post ... See more keywords
Introduction to Bioinformatics Resources for Post-transcriptional Regulation of Gene Expression.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1851-6_1
Abstract: Untranslated regions of mRNA (UTRs) are involved in defining the fate of the transcript through processes such as mRNA localization, degradation, translation initiation regulation, and several others: the action of trans-factors such as RNA-binding proteins… read more here.
Keywords: introduction bioinformatics; post transcriptional; bioinformatics resources; resources post ... See more keywords
Evaluation of Post-transcriptional Gene Regulation in Pancreatic Cancer Cells: Studying RNA Binding Proteins and Their mRNA Targets.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8879-2_22
Abstract: Post-transcriptional regulation of gene expression through interaction between RNA binding proteins (RBPs) and target mRNAs have gained considerable interest over the last decade. Altered expression of RBPs as detected in pancreatic ductal adenocarcinoma (PDAC) cells… read more here.
Keywords: binding proteins; post transcriptional; rna binding; biology ... See more keywords
Post-transcriptional regulation of MMP2 mRNA by its interaction with miR-20a and Nucleolin in breast cancer cell lines.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular biology reports"
DOI: 10.1007/s11033-021-06261-9
Abstract: Matrix-metalloproteinase-2 (MMP2) is a foremost MMP, governing invasion of breast cancer cells during metastasis. miR-20a was reported to induce mesenchymal to epithelial transition in MDA-MB-231 cells and its endogenous expression varies directly with invasiveness of… read more here.
Keywords: mir 20a; mmp2; post transcriptional; breast cancer ... See more keywords
PCSK9 post-transcriptional regulation: Role of a 3'UTR microRNA-binding site variant in linkage disequilibrium with c.1420G.
Sign Up to like & getrecommendations! Published in 2020 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2020.10.010
Abstract: BACKGROUND AND AIMS Proprotein convertase subtilisin/kexin type 9 (PCSK9) plays a crucial role in cholesterol homeostasis. A common variant, the G allele in position c.1420 (c.1420G), has been associated with a decrease of both plasma… read more here.
Keywords: transcriptional regulation; hsa mir; post transcriptional; pcsk9 ... See more keywords
Harnessing CRISPR/Cas systems for programmable transcriptional and post-transcriptional regulation.
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology advances"
DOI: 10.1016/j.biotechadv.2017.11.008
Abstract: Genome editing has enabled broad advances and novel approaches in studies of gene function and structure; now, emerging methods aim to precisely engineer post-transcriptional processes. Developing precise, efficient molecular tools to alter the transcriptome holds… read more here.
Keywords: systems programmable; crispr cas; post transcriptional; cas systems ... See more keywords