Post‐translational modifications of Arabidopsis E3 SUMO ligase AtSIZ1 are controlled by environmental conditions
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12309
Abstract: Sumoylation regulates numerous cellular functions in plants as well as in other eukaryotic systems. However, the regulatory mechanisms controlling E3 small ubiquitin‐related modifier (SUMO) ligase are not well understood. Here, post‐translational modification of the Arabidopsis… read more here.
Keywords: ligase atsiz1; sumo ligase; post translational; arabidopsis sumo ... See more keywords
Studying Reversible Protein Post‐translational Modification through Co‐translational Modification
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DOI: 10.1002/cbic.202200716
Abstract: Understanding the post‐translational modifications of targeted proteins is of great significance for manipulating the physiological processes of eukaryotes. Chemical biology tools have been used to investigate the biological roles of those post‐translational modifications at particular… read more here.
Keywords: modification; post translational; studying reversible; reversible protein ... See more keywords
Epiproteome profiling of cadmium‐transformed human bronchial epithelial cells by quantitative histone post‐translational modification–enzyme‐linked immunosorbent assay
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3597
Abstract: Cadmium (Cd), a carcinogenic toxic metal, is pervasively distributed in the soil, water and air. Chronic exposure to Cd has been correlated to lung disease development including cancers. Although many studies have been conducted to… read more here.
Keywords: post translational; epiproteome profiling; cadmium; histone post ... See more keywords
Fusaric Acid Induces DNA Damage and Post‐Translational Modifications of p53 in Human Hepatocellular Carcinoma (HepG2) Cells
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26037
Abstract: Fusaric acid (FA), a common fungal contaminant of maize, is known to mediate toxicity in plants and animals; however, its mechanism of action is unclear. p53 is a tumor suppressor protein that is activated in… read more here.
Keywords: dna damage; post translational; translational modifications; hepg2 cells ... See more keywords
Post‐translational regulation of muscle growth, muscle aging and sarcopenia
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13241
Abstract: Skeletal muscle makes up 30–40% of the total body mass. It is of great significance in maintaining digestion, inhaling and exhaling, sustaining body posture, exercising, protecting joints and many other aspects. Moreover, muscle is also… read more here.
Keywords: regulation muscle; translational regulation; post translational; muscle ... See more keywords
JUMPptm: Integrated software for sensitive identification of post‐translational modifications and its application in Alzheimer's disease study
Sign Up to like & getrecommendations! Published in 2022 at "PROTEOMICS"
DOI: 10.1002/pmic.202100369
Abstract: Background: Mass spectrometry (MS)‐based proteomic analysis of posttranslational modifications (PTMs) usually requires the pre‐enrichment of modified proteins or peptides. However, recent ultra‐deep whole proteome profiling generates millions of spectra in a single experiment, leaving many… read more here.
Keywords: jumpptm integrated; software sensitive; sensitive identification; post translational ... See more keywords
Thiol redox proteomics: Characterization of thiol-based post-translational modifications.
Sign Up to like & getrecommendations! Published in 2023 at "Proteomics"
DOI: 10.1002/pmic.202200194
Abstract: Redox post-translational modifications on cysteine thiols (redox PTMs) have profound effects on protein structure and function, thus enabling regulation of various biological processes. Redox proteomics approaches aim to characterize the landscape of redox PTMs at… read more here.
Keywords: redox proteomics; translational modifications; redox ptms; post translational ... See more keywords
Epstein-Barr virus regulates the life cycle and host cell biology by hijacking post-translational modification.
Sign Up to like & getrecommendations! Published in 2023 at "Reviews in medical virology"
DOI: 10.1002/rmv.2447
Abstract: Protein post-translational modifications (PTMs) are reversible processes that regulate the function of target proteins without altering their sequences. High-throughput sequencing surveys have provided insights into the patterns of PTMs, such as ubiquitination, SUMOylation, and phosphorylation.… read more here.
Keywords: post translational; epstein barr; host; host cell ... See more keywords
Histone Post-Translational Modifications and Nucleosome Organisation in Transcriptional Regulation: Some Open Questions.
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DOI: 10.1007/5584_2017_58
Abstract: The organisation of chromatin is first discussed to conclude that nucleosomes play both structural and transcription-regulatory roles. The presence of nucleosomes makes difficult the access of transcriptional factors to their target sequences and the action… read more here.
Keywords: organisation; modifications nucleosome; post translational; open questions ... See more keywords
Native Chromatin Proteomics (N-ChroP) to Characterize Histone Post-translational Modification (PTM) Combinatorics at Distinct Genomic Regions.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1597-3_14
Abstract: In this chapter, we describe the proteomic approach named "Native Chromatin Proteomics" (N-ChroP) that couples a modified Chromatin ImmunoPrecipitation (ChIP) protocol with the mass spectrometry (MS) analysis of immunoprecipitated proteins to study the combinatorial enrichment… read more here.
Keywords: post translational; chromatin proteomics; proteomics chrop; histone post ... See more keywords
Predicting Post-Translational Modifications from Local Sequence Fragments Using Machine Learning Algorithms: Overview and Best Practices.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6406-2_19
Abstract: Here, we present two perspectives on the task of predicting post translational modifications (PTMs) from local sequence fragments using machine learning algorithms. The first is the description of the fundamental steps required to construct a… read more here.
Keywords: machine; machine learning; local sequence; post translational ... See more keywords