Post‐translational modifications of Arabidopsis E3 SUMO ligase AtSIZ1 are controlled by environmental conditions
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12309
Abstract: Sumoylation regulates numerous cellular functions in plants as well as in other eukaryotic systems. However, the regulatory mechanisms controlling E3 small ubiquitin‐related modifier (SUMO) ligase are not well understood. Here, post‐translational modification of the Arabidopsis… read more here.
Keywords: ligase atsiz1; sumo ligase; post translational; arabidopsis sumo ... See more keywords
The logic of protein post‐translational modifications (PTMs): Chemistry, mechanisms and evolution of protein regulation through covalent attachments
Sign Up to like & getrecommendations! Published in 2024 at "BioEssays"
DOI: 10.1002/bies.202300178
Abstract: Protein post‐translational modifications (PTMs) play a crucial role in all cellular functions by regulating protein activity, interactions and half‐life. Despite the enormous diversity of modifications, various PTM systems show parallels in their chemical and catalytic… read more here.
Keywords: chemistry; translational modifications; protein post; logic ... See more keywords
Short‐chain acyl post‐translational modifications in cancers: Mechanisms, roles, and therapeutic implications
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DOI: 10.1002/cac2.70048
Abstract: Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific… read more here.
Keywords: short chain; translational modifications; post translational; chain acyl ... See more keywords
Studying Reversible Protein Post‐translational Modification through Co‐translational Modification
Sign Up to like & getrecommendations! Published in 2023 at "ChemBioChem"
DOI: 10.1002/cbic.202200716
Abstract: Understanding the post‐translational modifications of targeted proteins is of great significance for manipulating the physiological processes of eukaryotes. Chemical biology tools have been used to investigate the biological roles of those post‐translational modifications at particular… read more here.
Keywords: modification; post translational; studying reversible; reversible protein ... See more keywords
Cracking Lysine Crotonylation (Kcr): Enlightening a Promising Post‐Translational Modification
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DOI: 10.1002/cbic.202400639
Abstract: Lysine crotonylation (Kcr) is a recently discovered post‐translational modification (PTM). Both histone and non‐histone Kcr‐proteins have been associated with numerous diseases including cancer, acute kidney injury, HIV latency, and cardiovascular disease. Histone Kcr enhances gene… read more here.
Keywords: crotonylation; kcr; translational modification; crotonylation kcr ... See more keywords
Recombinant Monoclonal Antibodies for Detecting the Tubulin Post-Translational Modifications Glutamylation and Lysine-40 Acetylation.
Sign Up to like & getrecommendations! Published in 2025 at "Cytoskeleton"
DOI: 10.1002/cm.70011
Abstract: Post-translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine-40 (K40) on α-tubulin… read more here.
Keywords: translational modifications; glutamylation; tubulin; post translational ... See more keywords
Epiproteome profiling of cadmium‐transformed human bronchial epithelial cells by quantitative histone post‐translational modification–enzyme‐linked immunosorbent assay
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3597
Abstract: Cadmium (Cd), a carcinogenic toxic metal, is pervasively distributed in the soil, water and air. Chronic exposure to Cd has been correlated to lung disease development including cancers. Although many studies have been conducted to… read more here.
Keywords: post translational; epiproteome profiling; cadmium; histone post ... See more keywords
Fusaric Acid Induces DNA Damage and Post‐Translational Modifications of p53 in Human Hepatocellular Carcinoma (HepG2) Cells
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26037
Abstract: Fusaric acid (FA), a common fungal contaminant of maize, is known to mediate toxicity in plants and animals; however, its mechanism of action is unclear. p53 is a tumor suppressor protein that is activated in… read more here.
Keywords: dna damage; post translational; translational modifications; hepg2 cells ... See more keywords
Post‐translational regulation of muscle growth, muscle aging and sarcopenia
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13241
Abstract: Skeletal muscle makes up 30–40% of the total body mass. It is of great significance in maintaining digestion, inhaling and exhaling, sustaining body posture, exercising, protecting joints and many other aspects. Moreover, muscle is also… read more here.
Keywords: regulation muscle; translational regulation; post translational; muscle ... See more keywords
JUMPptm: Integrated software for sensitive identification of post‐translational modifications and its application in Alzheimer's disease study
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DOI: 10.1002/pmic.202100369
Abstract: Background: Mass spectrometry (MS)‐based proteomic analysis of posttranslational modifications (PTMs) usually requires the pre‐enrichment of modified proteins or peptides. However, recent ultra‐deep whole proteome profiling generates millions of spectra in a single experiment, leaving many… read more here.
Keywords: jumpptm integrated; software sensitive; sensitive identification; post translational ... See more keywords
Thiol redox proteomics: Characterization of thiol-based post-translational modifications.
Sign Up to like & getrecommendations! Published in 2023 at "Proteomics"
DOI: 10.1002/pmic.202200194
Abstract: Redox post-translational modifications on cysteine thiols (redox PTMs) have profound effects on protein structure and function, thus enabling regulation of various biological processes. Redox proteomics approaches aim to characterize the landscape of redox PTMs at… read more here.
Keywords: redox proteomics; translational modifications; redox ptms; post translational ... See more keywords