Dabrafenib monotherapy for a recurrent BRAFV600E-mutated TTF-1-positive posterior pituitary tumor
Sign Up to like & getrecommendations! Published in 2022 at "Acta Neurochirurgica"
DOI: 10.1007/s00701-022-05109-w
Abstract: Posterior pituitary tumors (PPT) expressing thyroid transcription factor-1 (TTF-1) are extremely rare low-grade neoplasms. The recent discovery of BRAF mutations in these tumors offers a potential alternative treatment using targeted therapies. We present the case… read more here.
Keywords: monotherapy; braf; posterior pituitary; mutated ttf ... See more keywords
Primary tumors of the posterior pituitary: A systematic review
Sign Up to like & getrecommendations! Published in 2019 at "Reviews in Endocrine and Metabolic Disorders"
DOI: 10.1007/s11154-019-09484-1
Abstract: In 2017, the World Health Organization established that pituicytoma, granular cell tumor (GCT), spindle cell oncocytoma (SCO) and sellar ependymomas (SE) are posterior pituitary tumors (PPT). They probably arise from the pituicytes and may constitute… read more here.
Keywords: systematic review; posterior pituitary; primary tumors; tumors posterior ... See more keywords
Clinical-Pathological, Immunohistochemical, and Genetic Characterization of a Series of Posterior Pituitary Tumors.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of neuropathology and experimental neurology"
DOI: 10.1093/jnen/nlaa139
Abstract: Posterior pituitary tumors are supposed to represent the morphological spectrum of a single entity. Herein, we report the clinical-pathological, immunohistochemical, and genetic features of 5 spindle cell oncocytomas (SCOs), 3 pituicytomas, and 1 granular cell… read more here.
Keywords: pathological immunohistochemical; posterior pituitary; immunohistochemical genetic; pituitary tumors ... See more keywords
Molecular analysis of brazilian patients with combined pituitary hormone deficiency and orthotopic posterior pituitary lobe reveals eight different PROP1 alterations with three novel mutations
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Endocrinology"
DOI: 10.1111/cen.13430
Abstract: Mutations in PROP1, HESX1 and LHX3 are associated with combined pituitary hormone deficiency (CPHD) and orthotopic posterior pituitary lobe (OPP). read more here.
Keywords: orthotopic posterior; posterior pituitary; pituitary hormone; pituitary lobe ... See more keywords
Whole Exome Sequencing in Patients With Ectopic Posterior Pituitary.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the Endocrine Society"
DOI: 10.1210/jendso/bvac116
Abstract: Context Ectopic posterior pituitary (EPP), a condition in which the posterior pituitary gland is displaced due to defective neuronal migration, is frequently associated with hypopituitarism. Genetic variants play a role, but many cases remain unexplained.… read more here.
Keywords: epp; ectopic posterior; associated epp; whole exome ... See more keywords
Recommendation to improve the WHO classification of posterior pituitary tumors as a unique entity: evidence from a large case series
Sign Up to like & getrecommendations! Published in 2022 at "Endocrine Connections"
DOI: 10.1530/ec-22-0188
Abstract: Introduction Most studies reporting posterior pituitary tumors (PPTs) are small case series or single cases. Methods Patients with a histological diagnosis of PPT from January 2010 to December 2021 in a tertiary center were identified.… read more here.
Keywords: case series; posterior pituitary; pituitary tumors; recommendation improve ... See more keywords
Posterior pituitary neurohormonal disturbances in schizophrenia and role of oxytocin in treatment – need for more short- and long-term studies
Sign Up to like & getrecommendations! Published in 2018 at "Neuropsychiatric Disease and Treatment"
DOI: 10.2147/ndt.s183645
Abstract: and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove… read more here.
Keywords: neuropsychiatric disease; treatment; posterior pituitary; neurohormonal disturbances ... See more keywords
Hyponatremia with Loss of High Signal Intensity in the Posterior Pituitary Lobe on T1-weighted Magnetic Resonance Imaging
Sign Up to like & getrecommendations! Published in 2017 at "Internal Medicine"
DOI: 10.2169/internalmedicine.8616-16
Abstract: Herein, we report on an 82-year-old woman who presented with anorexia. The patient had hyponatremia with preserved urinary osmotic pressure. T1-weighted magnetic resonance imaging (MRI) showed a lack of high signal intensity (SI) in the… read more here.
Keywords: resonance imaging; weighted magnetic; magnetic resonance; posterior pituitary ... See more keywords