Mediator complex component MED13 regulates zygotic genome activation and is required for postimplantation development in the mouse†, ‡
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DOI: 10.1093/biolre/ioy004
Abstract: Abstract Understanding factors that regulate zygotic genome activation (ZGA) is critical for determining how cells are reprogrammed to become totipotent or pluripotent. There is limited information regarding how this process occurs physiologically in early mammalian… read more here.
Keywords: genome activation; zygotic genome; med13; mediator complex ... See more keywords