A multicenter phase II trial of neoadjuvant letrozole plus low‐dose cyclophosphamide in postmenopausal patients with estrogen receptor‐positive breast cancer (JBCRG‐07): therapeutic efficacy and clinical implications of circulating endothelial cells
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Medicine"
DOI: 10.1002/cam4.1516
Abstract: Neoadjuvant endocrine therapy has been reported to decrease tumor size, which leads to increased breast conservation rates. To improve the clinical response, metronomic chemotherapy with endocrine therapy is a promising strategy. A multicenter phase II… read more here.
Keywords: breast; receptor positive; positive breast; postmenopausal ... See more keywords
The association of prediagnostic circulating levels of cardiometabolic markers, testosterone and sex hormone‐binding globulin with risk of breast cancer among normal weight postmenopausal women in the UK Biobank
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Cancer"
DOI: 10.1002/ijc.33508
Abstract: Emerging evidence suggests that normal weight postmenopausal women with a relative excess of body fat are at increased breast cancer risk. However, little is known about the associations between obesity‐related blood markers and risk of… read more here.
Keywords: risk; normal weight; breast cancer; postmenopausal ... See more keywords
Endometriosis in the postmenopausal female: clinical presentation, imaging features, and management
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DOI: 10.1007/s00261-019-02309-4
Abstract: Postmenopausal endometriosis is an important clinical entity which is likely under-recognized and in which the Radiologist can play a valuable role. In this review, we describe the clinical presentation and management of postmenopausal endometriosis, appraising… read more here.
Keywords: endometriosis; postmenopausal endometriosis; management; postmenopausal ... See more keywords
Denosumab mid-term densitometric gain in postmenopausal osteoporosis women in clinical practice: comment on “Variability of denosumab densitometric response in postmenopausal osteoporosis”
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DOI: 10.1007/s00296-018-4007-3
Abstract: We aim to confirm previous observations among postmenopausal osteoporotic women who received denosumab in terms of densitometric changes. We performed an observational clinical practice scenario study assessing baseline bone mineral density and its change after… read more here.
Keywords: densitometric gain; clinical practice; denosumab; postmenopausal ... See more keywords
A multiscale model to predict current absolute risk of femoral fracture in a postmenopausal population
Sign Up to like & getrecommendations! Published in 2019 at "Biomechanics and Modeling in Mechanobiology"
DOI: 10.1007/s10237-018-1081-0
Abstract: Osteoporotic hip fractures are a major healthcare problem. Fall severity and bone strength are important risk factors of hip fracture. This study aims to obtain a mechanistic explanation for fracture risk in dependence of these… read more here.
Keywords: risk; fracture; multiscale model; postmenopausal ... See more keywords
The synergistic effect between adult weight changes and CYP24A1 polymorphisms is associated with pre- and postmenopausal breast cancer risk
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DOI: 10.1007/s10549-019-05484-6
Abstract: Vitamin D (VD) metabolism regulates adipose tissue, lipogenesis inflammation, and tumor growth. CYP24A1 is the key enzyme for metabolic inactivation of active VD (1,25(OH)2D3). We examined whether common germline single nucleotide polymorphisms (SNPs) in the… read more here.
Keywords: risk; breast cancer; adult weight; postmenopausal ... See more keywords
Long-term excess body fat in adulthood and the risk of pre- and postmenopausal breast cancer in Chinese women
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DOI: 10.1007/s10549-020-05685-4
Abstract: Purpose This study aimed to investigate the association between long-term excess body fat and breast cancer risk by studying adult weight gain together with the subsequent weight fluctuations. Methods Weight gain measure in three different… read more here.
Keywords: risk; breast cancer; adult weight; postmenopausal ... See more keywords
An optimal intervention threshold of FRAX in postmenopausal Thai women
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DOI: 10.1007/s11657-022-01058-0
Abstract: Summary This study was designed to determine a FRAX intervention threshold in postmenopausal Thais, based on a history of hip fracture. The optimal FRAX thresholds for hip fracture were 4.9% (without BMD) and 4% (with… read more here.
Keywords: frax; bmd; postmenopausal; hip fracture ... See more keywords
Adherence to adjuvant endocrine therapy in postmenopausal breast cancer patients: A 5-year prospective study.
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DOI: 10.1016/j.breast.2019.01.003
Abstract: PURPOSE Adjuvant endocrine therapy (ET) in breast cancer reduces recurrence risk and increases overall survival. The aim of the study was to quantify non-adherence and discontinuation to ET in postmenopausal women with breast cancer, and… read more here.
Keywords: therapy; breast cancer; postmenopausal; cancer ... See more keywords
Regular physical activity reduces the proinflammatory response in older women with diabetes and hypertension in the postmenopausal phase
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DOI: 10.1016/j.exger.2021.111449
Abstract: Aging in women is characterized by extreme hormonal changes leading them to develop a chronic low-grade inflammation that is linked to the development of systemic arterial hypertension (SAH) and type 2 diabetes mellitus (T2DM). In… read more here.
Keywords: regular physical; postmenopausal; older women; hypertension ... See more keywords
Potential differences in somatosensory function during premenopause and early and late postmenopause in patients with burning mouth syndrome: An observational case–control study
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DOI: 10.1016/j.jds.2021.08.010
Abstract: Background/purpose Burning mouth syndrome (BMS) is a chronic condition presenting as intraoral burning or dysesthesia, with a high preponderance in menopausal women. This study aimed to examine the association between somatosensory dysfunction and BMS in… read more here.
Keywords: burning mouth; observational case; postmenopausal; function ... See more keywords