Anti‐Postmenopausal osteoporosis effects of Isopsoralen: A bioinformatics‐integrated experimental study
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7609
Abstract: Isopsoralen (IPRN), which comes from the fruit of Psoralea corylifolia, has been identified as a kind of phytoestrogen and has been proven to be effective for the treatment of osteoporosis (OP). However, the mechanisms underlying… read more here.
Keywords: iprn could; osteoporosis; postmenopausal osteoporosis; study ... See more keywords
Effects of prior osteoporosis treatment on the treatment response of romosozumab followed by denosumab in patients with postmenopausal osteoporosis
Sign Up to like & getrecommendations! Published in 2022 at "Osteoporosis International"
DOI: 10.1007/s00198-022-06386-y
Abstract: In patients with postmenopausal osteoporosis, prior osteoporosis treatment affected the bone mineral density increase of following treatment with 12 months of romosozumab, although it did not affect that of following treatment with 12 months of… read more here.
Keywords: patients postmenopausal; osteoporosis treatment; treatment; osteoporosis ... See more keywords
Denosumab mid-term densitometric gain in postmenopausal osteoporosis women in clinical practice: comment on “Variability of denosumab densitometric response in postmenopausal osteoporosis”
Sign Up to like & getrecommendations! Published in 2018 at "Rheumatology International"
DOI: 10.1007/s00296-018-4007-3
Abstract: We aim to confirm previous observations among postmenopausal osteoporotic women who received denosumab in terms of densitometric changes. We performed an observational clinical practice scenario study assessing baseline bone mineral density and its change after… read more here.
Keywords: densitometric gain; clinical practice; denosumab; postmenopausal ... See more keywords
Mild leukopenia following denosumab treatment in a woman with postmenopausal osteoporosis
Sign Up to like & getrecommendations! Published in 2018 at "Endocrine"
DOI: 10.1007/s12020-018-1699-9
Abstract: Denosumab, a fully human monoclonal antibody against receptor activator of nuclear factor kappaB ligand (RANKL), is considered an efficient and safe treatment of postmenopausal osteoporosis [1]. Its main adverse effects, including osteonecrosis of the jaw,… read more here.
Keywords: postmenopausal osteoporosis; treatment; denosumab; leukopenia following ... See more keywords
Predicting treatment recommendations in postmenopausal osteoporosis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of biomedical informatics"
DOI: 10.1016/j.jbi.2021.103780
Abstract: We designed, implemented, and tested a clinical decision support system at the Research Center for the Study of Menopause and Osteoporosis within the University of Ferrara (Italy). As an independent module of our system, we… read more here.
Keywords: system; treatment; treatment recommendations; predicting treatment ... See more keywords
Short-range UV-LED irradiation in postmenopausal osteoporosis using ovariectomized mice
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-86730-0
Abstract: Postmenopausal osteoporosis is crucial condition that reduces the QOL of affected patients just like aged type osteoporosis. The aim of this study was to evaluate the effectiveness of short-range UV-LED irradiation in postmenopausal osteoporosis using… read more here.
Keywords: postmenopausal osteoporosis; vit; vit group; irradiation ... See more keywords
Extracellular regulated kinase 5 mediates osteoporosis through modulating viability and apoptosis of osteoblasts in ovariectomized rats
Sign Up to like & getrecommendations! Published in 2019 at "Bioscience Reports"
DOI: 10.1042/bsr20190432
Abstract: Postmenopausal osteoporosis is a common condition characterized by the increase and activation of osteoclasts. The present study aimed to investigate the effects of extracellular signal-regulated kinase (ERK) 5 (ERK-5) on postmenopausal osteoporosis by regulating the… read more here.
Keywords: ovariectomized rats; postmenopausal osteoporosis; erk; viability ... See more keywords
Combination and sequential treatment in women with postmenopausal osteoporosis
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2020.1717468
Abstract: ABSTRACT Introduction: Since postmenopausal osteoporosis is a chronic, potentially disabling condition requiring long-term treatment, the physician is expected to decide the optimal treatment strategy, e.g. how to use the available osteoanabolic and antiresorptive agents, sequentially… read more here.
Keywords: combination; treatment women; treatment; sequential treatment ... See more keywords
microRNA-211-5p predicts the progression of postmenopausal osteoporosis and attenuates osteogenesis by targeting dual specific phosphatase 6
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2017626
Abstract: ABSTRACT Postmenopausal osteoporosis (PMOP) is known as one of the prevalent diseases among middle-aged and elderly women. This paper revolves around the alteration of miR-211-5p in PMOP patients and its function in osteogenic differentiation. Quantitative… read more here.
Keywords: mir 211; osteogenic differentiation; phosphatase; postmenopausal osteoporosis ... See more keywords
MiRNA-133a is involved in the regulation of postmenopausal osteoporosis through promoting osteoclast differentiation
Sign Up to like & getrecommendations! Published in 2018 at "Acta Biochimica et Biophysica Sinica"
DOI: 10.1093/abbs/gmy006
Abstract: The important role of miR-133a in the progress and development of postmenopausal osteoporosis has been reported, however, the underlying mechanism is not clear yet. In this study, qRT-PCR analysis was performed to assess miR-133 expression… read more here.
Keywords: mirna 133a; postmenopausal osteoporosis; differentiation; mir 133a ... See more keywords
Effects of Gushukang for postmenopausal osteoporosis
Sign Up to like & getrecommendations! Published in 2020 at "Medicine"
DOI: 10.1097/md.0000000000020908
Abstract: Abstract Background: Postmenopausal osteoporosis (PMO) is one of the most common systemic bone diseases with a high risk of fracture. Traditional herbal formula Gushukang (GSK) has been used to treat PMO. However, there is no… read more here.
Keywords: gsk; postmenopausal osteoporosis; effects gushukang; gushukang postmenopausal ... See more keywords