Articles with "postn" as a keyword



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Cancer cell‐derived novel periostin isoform promotes invasion in head and neck squamous cell carcinoma

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Published in 2023 at "Cancer Medicine"

DOI: 10.1002/cam4.5601

Abstract: It recently has been reported that partial‐epithelial–mesenchymal transition (p‐EMT) program is associated with metastasis in head and neck squamous cell carcinoma (HNSCC). We previously have identified POSTN (which encodes periostin) as an invasion‐promoting molecule in… read more here.

Keywords: cell; postn; iso5; isoform ... See more keywords
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POSTN promotes diabetic vascular calcification by interfering with autophagic flux.

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Published in 2021 at "Cellular signalling"

DOI: 10.1016/j.cellsig.2021.109983

Abstract: Autophagy is a lysosomal degradative process that is closely related to the pathogenesis of vascular calcification. Recent evidence suggests that periostin (POSTN) is a unique extracellular matrix protein that is associated with diabetic vascular complications.… read more here.

Keywords: diabetic vascular; vascular calcification; postn; calcification ... See more keywords
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Integrative Analysis of Periostin in Primary and Advanced Prostate Cancer

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Published in 2020 at "Translational Oncology"

DOI: 10.1016/j.tranon.2020.100789

Abstract: Periostin (POSTN) is an extracellular matrix protein associated with tumor progression and shorter survival in prostate cancer (PCa). Here, we performed an integrative analysis of POSTN’s role in patients with PCa. Clinical and POSTN data… read more here.

Keywords: integrative analysis; analysis; postn; prostate cancer ... See more keywords
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miR-876 Inhibits EMT and Liver Fibrosis via POSTN to Suppress Metastasis in Hepatocellular Carcinoma

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Published in 2020 at "BioMed Research International"

DOI: 10.1155/2020/1964219

Abstract: Background The asymptomatic onset, frequent recurrence, and poor prognosis of hepatocellular carcinoma (HCC) prompted us to identify new therapeutic targets or predictive markers of HCC diagnosis or prognosis. Methods In this study, bioinformatics analysis was… read more here.

Keywords: hepatocellular carcinoma; mir 876; hcc; fibrosis ... See more keywords

Abstract 521: Cardiac Fibroblasts are Activated During Postnatal Extracellular Matrix Remodeling

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Published in 2019 at "Circulation Research"

DOI: 10.1161/res.125.suppl_1.521

Abstract: Objectives: During the postnatal period, P0 to P30 in the mouse, the myocardial extracellular matrix (ECM) transitions to a mature profile necessary for increased cardiac output. We hypothesize that, during the postnatal period, cardiac fibroblasts… read more here.

Keywords: mcm r26; postn; r26 gfp; mcm ... See more keywords
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Salivary and serum periostin in kidney transplant recipients

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Published in 2023 at "PLOS ONE"

DOI: 10.1371/journal.pone.0285256

Abstract: Introduction End-stage renal disease (ESRD) treatment includes dialysis and kidney transplantation. Transplant rejection is a major barrier to transplant success. One of the markers mentioned in previous studies on renal function in patients with renal… read more here.

Keywords: salivary serum; serum; postn; kidney transplant ... See more keywords
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POSTN Secretion by Extracellular Matrix Cancer-Associated Fibroblasts (eCAFs) Correlates with Poor ICB Response via Macrophage Chemotaxis Activation of Akt Signaling Pathway in Gastric Cancer.

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Published in 2023 at "Aging and disease"

DOI: 10.14336/ad.2023.0503

Abstract: Immune checkpoint blockade (ICB) therapy has revolutionized cancer treatment, but its clinical benefit is limited in advanced gastric cancer (GC). Cancer-associated fibroblasts (CAFs) have been reported to be associated with ICB resistance, but the underlying… read more here.

Keywords: macrophage chemotaxis; postn; response; cancer ... See more keywords
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Confounding Patient Factors Affecting the Proper Interpretation of the Periostin Level as a Biomarker in Asthma Development

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Published in 2020 at "Journal of Asthma and Allergy"

DOI: 10.2147/jaa.s230892

Abstract: Introduction The proper use of serum periostin (POSTN) as a biomarker for asthma is hindered by inconsistent performance in different clinical settings. Objective To explore patient’s factors that may affect POSTN expression locally and systematically… read more here.

Keywords: biomarker asthma; asthma; level; postn ... See more keywords
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Knockdown of POSTN Inhibits Osteogenic Differentiation of Mesenchymal Stem Cells From Patients With Steroid-Induced Osteonecrosis

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Published in 2020 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2020.606289

Abstract: Steroid-induced osteonecrosis of femoral head (SONFH) is a common and serious complication caused by long-term and/or excessive use of glucocorticoids (GCs). The decreased activity and abnormal differentiation of bone marrow mesenchymal stem cells (BMSCs) are… read more here.

Keywords: sost; postn; expression; differentiation ... See more keywords
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Integrated Analysis Reveals the Gut Microbial Metabolite TMAO Promotes Inflammatory Hepatocellular Carcinoma by Upregulating POSTN

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Published in 2022 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2022.840171

Abstract: Liver cancer has a high mortality rate. Chronic inflammation is one of the leading causes of hepatocellular carcinoma. Recent studies suggested high levels of trimethylamine N-oxide (TMAO) may correlate with increased risk of inflammatory-induced liver… read more here.

Keywords: hepatocellular carcinoma; liver cancer; postn; tmao ... See more keywords
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Prognostic Impact of the Angiogenic Gene POSTN and Its Related Genes on Lung Adenocarcinoma

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.699824

Abstract: Background The function of angiogenesis-related genes (ARGs) in lung adenocarcinoma (LUAD) remains poorly documented. This study was designed to reveal ARGs in LUAD and related networks. Methods We worked with sequencing data and clinical information… read more here.

Keywords: lung adenocarcinoma; postn; gene postn; analysis ... See more keywords