Effects of SA237, a humanized anti-interleukin-6 receptor monoclonal antibody, on pre- and postnatal development in cynomolgus monkey.
Sign Up to like & getrecommendations! Published in 2017 at "Birth defects research"
DOI: 10.1002/bdr2.1036
Abstract: BACKGROUND SA237 is a humanized anti-interleukin-6 receptor (IL-6R) monoclonal antibody in which the constant and variable regions have been engineered for a longer plasma half-life. According to literature, blocking of IL-6 related functions could have… read more here.
Keywords: humanized anti; antibody; sa237 humanized; postnatal development ... See more keywords
Comparative Aspects of Pre‐ and Postnatal Development of the Male Reproductive System
Sign Up to like & getrecommendations! Published in 2018 at "Birth Defects Research"
DOI: 10.1002/bdr2.1133
Abstract: This review describes pre‐ and postnatal development of the male reproductive system in humans and laboratory animals, and highlights species differences in the timing and control of hormonal and morphologic events. Major differences are that… read more here.
Keywords: development male; male reproductive; pre postnatal; postnatal development ... See more keywords
The postnatal development of MT, V1, LGN, pulvinar and SC in prosimian galagos (Otolemur garnettii)
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24885
Abstract: Considerable evidence supports the premise that the visual system of primates develops hierarchically, with primary visual cortex developing structurally and functionally first, thereby influencing the subsequent development of higher cortical areas. An apparent exception is… read more here.
Keywords: lgn pulvinar; pulvinar; pulvinar prosimian; postnatal development ... See more keywords
Sexual dimorphism of microglia and synapses during mouse postnatal development
Sign Up to like & getrecommendations! Published in 2018 at "Developmental Neurobiology"
DOI: 10.1002/dneu.22568
Abstract: Microglia participate in synapse remodeling in the cortex and hippocampus during mouse postnatal development. Although sex differences in microglia activity during embryonic development have been reported in these regions, it remains unexplored whether microglia show… read more here.
Keywords: microglia; mouse postnatal; microglia synapses; postnatal development ... See more keywords
The expression and function of glutamate aspartate transporters in Bergmann glia are decreased in neuronal nitric oxide synthase‐knockout mice during postnatal development
Sign Up to like & getrecommendations! Published in 2022 at "Glia"
DOI: 10.1002/glia.24143
Abstract: Bergmann glia (BG) predominantly use glutamate/aspartate transporters (GLAST) for glutamate uptake in the cerebellum. Recently, nitric oxide (NO) treatment has been shown to upregulate GLAST function and increase glutamate uptake in vitro. We previously discovered… read more here.
Keywords: nitric oxide; expression; postnatal development; mice ... See more keywords
NMDA receptor activity during postnatal development determines intrinsic excitability and mossy fiber long-term potentiation of CA3 pyramidal cells.
Sign Up to like & getrecommendations! Published in 2023 at "Hippocampus"
DOI: 10.1002/hipo.23524
Abstract: Experimental manipulations that interfere with the functional expression of N-methyl-D-aspartate receptors (NMDARs) during prenatal neurodevelopment or critical periods of postnatal development are models that mimic behavioral and neurophysiological abnormalities of schizophrenia. Blockade of NMDARs with… read more here.
Keywords: long term; term potentiation; postnatal development;
Bisphenol A exposure induces testicular oxidative damage via FTO/m6A/Nrf2 axis during postnatal development in mice
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4417
Abstract: Bisphenol A (BPA), a commonly used plasticizer in the production of polycarbonate plastics and epoxy resins, has been shown to induce male reproductive toxicity. However, the effects of BPA exposure on early testicular development have… read more here.
Keywords: development; postnatal development; testicular oxidative; m6a ... See more keywords
Dipeptidyl Peptidase 4 Inhibitors Diprotin A and Sitagliptin Administered on Weeks 2-3 of Postnatal Development Modulate Monoamine Metabolism in the Striatum of Adult Rats
Sign Up to like & getrecommendations! Published in 2017 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-017-3763-5
Abstract: The levels of monoamines and their metabolites in brain structures of adult (3-month-old) rats with emotional and motivational disorders induced by inhibitors of dipeptidyl peptidase 4 (DPP-4; EC 3.4.14.5) diprotin A and sitagliptin on weeks… read more here.
Keywords: weeks postnatal; adult rats; dipeptidyl peptidase; diprotin sitagliptin ... See more keywords
Early Postnatal Development of the Lamination in the Lateral Geniculate Nucleus A-Layers in Cats
Sign Up to like & getrecommendations! Published in 2018 at "Cellular and Molecular Neurobiology"
DOI: 10.1007/s10571-018-0585-6
Abstract: The early postnatal development of the A-layers of the dorsal lateral geniculate nucleus (LGNd) was investigated in kittens aged 0–34 days by immunohistochemistry for the selective marker for neuronal differentiation (NeuN protein) and parvalbumin. We report… read more here.
Keywords: geniculate nucleus; lateral geniculate; early postnatal; geniculate ... See more keywords
In Utero Exposure to trans-10, cis-12 Conjugated Linoleic Acid Modifies Postnatal Development of the Mammary Gland and its Hormone Responsiveness
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Mammary Gland Biology and Neoplasia"
DOI: 10.1007/s10911-021-09499-y
Abstract: We previously showed that dietary trans-10, cis-12 conjugated linoleic acid (10,12 CLA) stimulates estrogen-independent mammary growth in young ovariectomized mice. Here we investigated the effects of in utero or postnatal exposure to cis-9, trans-11 (9,11… read more here.
Keywords: mammary gland; development mammary; postnatal development; exposure ... See more keywords
Primary observation of the role of posttranslational modification of dentin sialophosphoprotein (DSPP) on postnatal development of mandibular condyle in mice.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2021.105086
Abstract: OBJECTIVES We aimed to observe the posttranslational role of dentin sialophosphoprotein (DSPP) on postnatal development of mandibular condyle in mice. METHODS To explore the function of full-length DSPP, four groups of mice were employed: (1)… read more here.
Keywords: mandibular condyle; dspp postnatal; dspp; role ... See more keywords