Influence of cerebrospinal fluid drainage and other variables on the plasma vancomycin trough levels in postoperative neurosurgical patients
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Neurosurgery"
DOI: 10.1080/02688697.2020.1769023
Abstract: Abstract Background Therapeutic drug monitoring (TDM) aims to minimise the clinical impact of vancomycin (VCM) pharmacokinetic variability. However, TDM data are limited among specific patient populations, including postoperative neurosurgical populations. The objective of this study… read more here.
Keywords: trough levels; postoperative neurosurgical; group; drainage ... See more keywords
Population pharmacokinetic model of vancomycin in postoperative neurosurgical patients
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DOI: 10.3389/fphar.2022.1005791
Abstract: Objective: Vancomycin is commonly used in postoperative neurosurgical patients for empirical anti-infective treatment due to the low success rate of bacterial culture in cerebrospinal fluid (about 20%) and the high mortality of intracranial infection. At… read more here.
Keywords: vancomycin; population pharmacokinetic; postoperative neurosurgical; model ... See more keywords