SIRT1 reduces epigenetic and non-epigenetic changes to maintain the quality of postovulatory aged oocytes in mice.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2020.112421
Abstract: Postovulatory oocyte aging has a major influence on the development potential of embryos. Many antioxidants can delay oocyte aging by regulating the expression of SIRT1. However, there is a lack of knowledge on SIRT1 function… read more here.
Keywords: sirt1; oocyte aging; postovulatory aged; epigenetic changes ... See more keywords
Supplementation of nicotinamide mononucleotide improves the quality of postovulatory aged porcine oocytes
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Molecular Cell Biology"
DOI: 10.1093/jmcb/mjac025
Abstract: Supplementary Materials and methods Porcine oocyte collection and in vitro maturation Abattoir-derived porcine ovaries were transported to the laboratory within 2 h in a physiological saline containing penicillin G/streptomycin sulphate. Cumulus-oocyte complexes (COCs) were isolated… read more here.
Keywords: nicotinamide mononucleotide; supplementation nicotinamide; improves quality; postovulatory ... See more keywords