BRAF‐V600E utilizes posttranscriptional mechanisms to amplify LPS‐induced TNFα production in dendritic cells in a mouse model of Langerhans cell histiocytosis
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DOI: 10.1002/jlb.3a0122-075rr
Abstract: Langerhans cell histiocytosis (LCH) is an inflammatory disease characterized by abnormal dendritic cells (DCs) with hyperactive ERK signaling, called “LCH cells.” Since DCs rely on ERK signaling to produce inflammatory molecules in response to pathogenic… read more here.
Keywords: tnf production; tnf; biology; induced tnf ... See more keywords