Identification of Native and Posttranslationally Modified HLA‐B*57:01‐Restricted HIV Envelope Derived Epitopes Using Immunoproteomics
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DOI: 10.1002/pmic.201700253
Abstract: The recognition of pathogen‐derived peptides by T lymphocytes is the cornerstone of adaptive immunity, whereby intracellular antigens are degraded in the cytosol and short peptides assemble with class I human leukocyte antigen (HLA) molecules in… read more here.
Keywords: modified hla; envelope; hla; identification native ... See more keywords
Characterization of Histidine Functionalization and Its Timing in the Biosynthesis of Ribosomally Synthesized and Posttranslationally Modified Thioamitides.
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DOI: 10.1021/jacs.1c11669
Abstract: Thioamitides are ribosomally synthesized and posttranslationally modified peptide (RiPP) natural products that hold great potential in anticancer drug development. Members in this RiPP family feature a thioamidated peptidyl chain conjugated with a macrocyclic ring system… read more here.
Keywords: biosynthesis; posttranslationally modified; ribosomally synthesized; functionalization ... See more keywords
Chlamydia Hijacks ARF GTPases To Coordinate Microtubule Posttranslational Modifications and Golgi Complex Positioning
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DOI: 10.1128/mbio.02280-16
Abstract: ABSTRACT The intracellular bacterium Chlamydia trachomatis develops in a parasitic compartment called the inclusion. Posttranslationally modified microtubules encase the inclusion, controlling the positioning of Golgi complex fragments around the inclusion. The molecular mechanisms by which… read more here.
Keywords: inclusion; golgi complex; around inclusion; chlamydia ... See more keywords