Cascade C-H Annulation of Aldoximes with Alkynes Using O2 as the Sole Oxidant: One-Pot Access to Multisubstituted Protoberberine Skeletons.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.6b03772
Abstract: A cascade double C-H annulation of aldoximes with alkynes to produce benz[a]acridizinium salts is developed by using a simple catalytic system of [Cp*Rh(OAc)2]2 in the presence of Zn(OTf)2 with oxygen as the sole oxidant. In… read more here.
Keywords: aldoximes alkynes; sole oxidant; annulation aldoximes; pot access ... See more keywords
One-Pot Access to peri-Condensed Heterocycles via Manganese-Catalyzed Cascade C-N and C-C Bond Formation.
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DOI: 10.1021/acs.orglett.8b01586
Abstract: A Mn(III)-catalyzed three-component cascade C-H/N-H functionalization of 2-aminopyridines with 2 equiv of dialkyl butyndioates leads to peri-condensed tricylic azines through a selective, but partly destructive, stoichiometry. A wide range of 2,11-diazatricyclo[5.3.1.04,11]undeca-1(10),4,6,8-tetraen-3-ones were thus obtained with… read more here.
Keywords: access peri; peri condensed; cascade; pot access ... See more keywords
Fusion of Aromatic Ring to Azoarenes: One-Pot Access to 5,6-Phenanthroliniums for Mitochondria-Targeted Far-Red/NIR Fluorescent Probes.
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DOI: 10.1021/acs.orglett.8b04072
Abstract: Disclosed herein is a highly efficient strategy to fuse an aromatic ring to azoarenes for one-pot access to 5,6-phenanthrolinium skeletons via tandem ortho-C-H arylation and aryl quaternization. This protocol enables ortho-hindered azobenzenes to solely form… read more here.
Keywords: ring azoarenes; azoarenes one; aromatic ring; pot access ... See more keywords
Pd-catalyzed imine-directed one-pot access to polysubstituted pyrroles via tandem triple isocyanide insertion/aza-Nazarov cyclization reactions
Sign Up to like & getrecommendations! Published in 2023 at "Organic Chemistry Frontiers"
DOI: 10.1039/d3qo00598d
Abstract: Herein, we report a novel one-pot method for synthesizing polysubstituted pyrrole derivatives via three-component reactions of alkenyl bromides, amines, and isocyanides. The conversion process is catalyzed by a Pd catalyst... read more here.
Keywords: catalyzed imine; imine directed; one pot; directed one ... See more keywords