An efficient cyclization of lapachol to new benzo[h]chromene hybrid compounds: a stepwise vs. one-pot esterification-click (CuAAC) study
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DOI: 10.1039/c8nj03699c
Abstract: A straightforward one-pot vs. stepwise esterification of lapachol was performed to obtain highly diversified heterocycles. Whereas the one-pot esterification leads to mono esterified lapachol, the stepwise approach generated benzo[h]chromene. Furthermore, benzo[h]chromene architectures with embedded triazole… read more here.
Keywords: benzo chromene; pot esterification; one pot;