One-pot four-component synthesis of thiazolidin-2-imines using CuI/ZnII dual catalysis: A new class of acetylcholinesterase inhibitors.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2018.12.002
Abstract: An efficient one-pot four-component strategy involving aldehydes, amines, alkynes and isothiocyanates has been developed to access a novel series of thiazolidine-2-imines (5a-x). This process operates under the action of a cooperative catalysis composed of Cu(I)… read more here.
Keywords: four component; catalysis; pot four; one pot ... See more keywords
Development of a One-Pot Four C-C Bond-Forming Sequence Based on Palladium/Ruthenium Tandem Catalysis.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.7b03556
Abstract: A one-pot four C-C bond-forming sequence has been developed using two distinct transition metal complexes. The sequence entails a double Pd-catalyzed allylic alkylation followed by a Ru-catalyzed ring-closing metathesis and a Pd-catalyzed Heck coupling. The… read more here.
Keywords: bond; four bond; pot four; one pot ... See more keywords
β-Cyclodextrin catalyzed one-pot four component auspicious protocol for synthesis of spiro[acridine-9,3′-indole]-2′,4,4′(1′H,5′H,10H)-trione as a potential antimicrobial agent
Sign Up to like & getrecommendations! Published in 2018 at "Synthetic Communications"
DOI: 10.1080/00397911.2017.1421665
Abstract: ABSTRACT We have developed an perceptive and facile approach for the synthesis of new spiro[acridine-9,3′-indole]-2′,4,4′(1′H,5′H,10H)-trione derivatives (4a–t) by one-pot four component condensation involving two equivalence of dimedone (1), substituted anilines (2a–t), and isatin (3) catalyzed… read more here.
Keywords: indole 10h; acridine indole; spiro acridine; pot four ... See more keywords
Novel one-pot four-component condensation cyclization reactions for the synthesis of thiazolidine-4-one and 3H-thiazoles
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Sulfur Chemistry"
DOI: 10.1080/17415993.2018.1497168
Abstract: ABSTRACT A novel, simple and efficient synthetic protocol has been developed for the synthesis of a series of thiazolidine-4-one and 3H-thiazole derivatives via a one-pot four-component condensation-cyclization reaction of hydrazine with allyl isothiocyanate and an… read more here.
Keywords: four component; thiazolidine one; pot four; one pot ... See more keywords