One-pot Multicomponent Synthesis of Highly Functionalized 1,4-Dihydropyridines Using Porcine Pancreatic Lipase
Sign Up to like & getrecommendations! Published in 2019 at "Chemical Research in Chinese Universities"
DOI: 10.1007/s40242-019-8277-4
Abstract: A series of highly functionalized 1,4-dihydropyridines was synthesized via one-pot multicomponent reactions of aromatic aldehyde, malononitrile and N-methyl-1-(methylthio)-2-nitroethenamine using Porcine pancreatic lipase(PPL) as catalyst in DMSO. This protocol is featured by mild reaction conditions, simple… read more here.
Keywords: porcine pancreatic; highly functionalized; pot multicomponent; using porcine ... See more keywords
Graphene oxide: A carbocatalyst for the one-pot multicomponent synthesis of highly functionalized tetrahydropyridines
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2017.05.067
Abstract: Abstract A simple, straightforward and efficient methodology is described for the synthesis of polysubstituted tetrahydropyridine via one-pot multicomponent reaction of β-ketoester, aldehyde and aniline in presence of catalytic amount of graphene oxide in acetonitrile. Graphene… read more here.
Keywords: graphene oxide; pot multicomponent; synthesis; one pot ... See more keywords
One-pot multicomponent synthesis of 1,2,3,4-tetrasubstituted pyrroles catalyzed by [NMPH]CH3SO3
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2019.151043
Abstract: Abstract A general method for the synthesis of 1,2,3,4-tetrasubstituted pyrroles by [NMPH]CH3SO3 is reported. A full factorial design was performed in order to obtain a more robust and statistically correct optimum condition. The products were… read more here.
Keywords: tetrasubstituted pyrroles; pot multicomponent; synthesis tetrasubstituted; nmph ch3so3 ... See more keywords
Stereoselective Synthesis of Spirooxindole Derivatives Using One-Pot Multicomponent Cycloaddition Reaction and Evaluation of Their Antiproliferative Efficacy
Sign Up to like & getrecommendations! Published in 2020 at "ACS Omega"
DOI: 10.1021/acsomega.0c03675
Abstract: A highly stereoselective, one-pot, multicomponent method has been developed to synthesize pyrrolizidine- and N-methyl pyrrolidine-substituted spirooxindole derivatives. The [3 + 2] cycloaddition reaction involves the reaction between the dipole azomethine ylides, generated in situ from… read more here.
Keywords: pot multicomponent; antiproliferative efficacy; reaction; one pot ... See more keywords
Microwave-assisted MgO NP catalyzed one-pot multicomponent synthesis of polysubstituted steroidal pyridines
Sign Up to like & getrecommendations! Published in 2018 at "New Journal of Chemistry"
DOI: 10.1039/c7nj03742b
Abstract: The present study reports a highly efficient and green synthetic route for the synthesis of steroidal pyridines. The synthetic methodology involves a microwave-assisted one-pot multicomponent reaction using MgO NPs as a heterogeneous, mild and reusable… read more here.
Keywords: pot multicomponent; steroidal pyridines; microwave assisted; one pot ... See more keywords
Expeditious one-pot multicomponent microwave-assisted green synthesis of substituted 2-phenyl Quinoxaline and 7-bromo-3-(4-ethylphenyl) pyrido[2,3-b]pyrazine in water–PEG and water–ethanol
Sign Up to like & getrecommendations! Published in 2017 at "Synthetic Communications"
DOI: 10.1080/00397911.2017.1337153
Abstract: ABSTRACT An eco-friendly, expeditious one-pot multicomponent synthesis of substituted 2-phenyl quinoxaline and 7-bromo-3-(4-ethylphenyl) pyrido[2,3-b]pyrazine 4a–k in water–ethanol from easily available starting materials as acetophenone 1, succinamide 2, aromatic amine 3, in situ-generated α-iodo acetophenone from… read more here.
Keywords: pot multicomponent; expeditious one; water; synthesis substituted ... See more keywords
Cu(OAc)2 Catalyzed Synthesis of Novel Chromeno [4,3-b]Pyrano[3,4-e]Pyridine-6,8-Dione Derivatives via a One-Pot Multicomponent Reaction in Water under Mild Reaction Conditions
Sign Up to like & getrecommendations! Published in 2020 at "Polycyclic Aromatic Compounds"
DOI: 10.1080/10406638.2020.1866037
Abstract: An efficient method is introduced based on the copper(II) acetate catalyzed one-pot multicomponent synthesis of novel chromeno[4,3-b]pyrano[3,4-e]pyridine-6,8-dione derivatives under mild reaction ... read more here.
Keywords: synthesis novel; pot multicomponent; chromeno pyrano; reaction ... See more keywords
One-Pot Multicomponent Reactions in Deep Eutectic Solvents
Sign Up to like & getrecommendations! Published in 2023 at "Current Organic Chemistry"
DOI: 10.2174/1385272827666230427101210
Abstract: The increasing environmental pollution and its detrimental impact on the ecosystem made scientists develop new chemical strategies involving eco-friendly chemicals, solvents, catalysts, atom-economical procedures, and alternative energy sources. Among these, deep eutectic solvents (DESs) are… read more here.
Keywords: deep eutectic; multicomponent reactions; pot multicomponent; one pot ... See more keywords
One-pot multicomponent green Hantzsch synthesis of 1,2-dihydropyridine derivatives with antiproliferative activity
Sign Up to like & getrecommendations! Published in 2020 at "Beilstein Journal of Organic Chemistry"
DOI: 10.3762/bjoc.16.235
Abstract: A rapid route for obtaining unsymmetrical 1,2-dihydropyridines (1,2-DHPs) as opposed to 1,4-dihydropyridines (1,4-DHPs) has been achieved via a one-pot multicomponent Hantzsch reaction. A benign protocol has been developed for the preparation of various 1,2-dihydropyridine derivatives… read more here.
Keywords: pot multicomponent; dihydropyridine derivatives; antiproliferative activity; one pot ... See more keywords