Potassium-selective channelrhodopsins can exert hyper- or depolarizing effects in excitable cells of Caenorhabditis elegans, depending on experimental conditions.
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DOI: 10.1093/genetics/iyaf083
Abstract: Among the most frequent applications of optogenetic tools are those for depolarization of excitable cells such as neurons and muscles. Equally important are inhibitory tools that act through cellular hyperpolarization, which often rely on chloride… read more here.
Keywords: hyperpolarization; selective channelrhodopsins; excitable cells; illumination ... See more keywords
Structural Foundations of Potassium Selectivity in Channelrhodopsins
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DOI: 10.1128/mbio.03039-22
Abstract: Recently discovered microbial light-gated ion channels (channelrhodopsins) with a higher permeability for K+ than for Na+ (potassium-selective channelrhodopsins [kalium channelrhodopsins, or KCRs]) demonstrate an alternative K+ selectivity mechanism, unrelated to well-characterized “selectivity filters” of voltage-… read more here.
Keywords: potassium selective; selectivity; channelrhodopsins kcrs; selective channelrhodopsins ... See more keywords
High-Performance Potassium-Selective Biosensor Platform Based on Resistive Coupling of a-IGZO Coplanar-Gate Thin-Film Transistor
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DOI: 10.3390/ijms24076164
Abstract: The potassium (K+) ion is an essential mineral for balancing body fluids and electrolytes in biological systems and regulating bodily function. It is associated with various disorders. Given that it exists at a low concentration… read more here.
Keywords: potassium; biosensor platform; resistive coupling; potassium selective ... See more keywords