Research progress on substitution of in vivo method(s) by in vitro method(s) for human vaccine potency assays.
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DOI: 10.1080/14760584.2023.2178421
Abstract: INTRODUCTION : Potency is a critical quality attribute for controlling quality consistency and relevant biological properties of vaccines. Owing to the high demand for animals, lengthy operations and high variability of in vivo methods, in… read more here.
Keywords: vitro; vaccine potency; potency; potency assays ... See more keywords
In vitro immunotherapy potency assays using real-time cell analysis
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DOI: 10.1371/journal.pone.0193498
Abstract: A growing understanding of the molecular interactions between immune effector cells and target tumor cells, coupled with refined gene therapy approaches, are giving rise to novel cancer immunotherapeutics with remarkable efficacy in the clinic against… read more here.
Keywords: potency; immunotherapy; tumor cells; time ... See more keywords
Potency Assays for Mesenchymal Stromal Cell Secretome-Based Products for Tissue Regeneration
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DOI: 10.3390/ijms24119379
Abstract: Adult stem cells maintaining tissue homeostasis and regeneration are tightly regulated by their specific microenvironments or stem cell niches. The dysfunction of niche components may alter the activity of stem cells and ultimately lead to… read more here.
Keywords: regeneration; cell; potency; potency assays ... See more keywords