Articles with "potency preclinical" as a keyword



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In Vitro Potency and Preclinical Pharmacokinetic Comparison of All-D-Enantiomeric Peptides Developed for the Treatment of Alzheimer’s Disease

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Published in 2018 at "Journal of Alzheimer's Disease"

DOI: 10.3233/jad-180165

Abstract: Diffusible amyloid-β (Aβ) oligomers are currently presumed to be the most cytotoxic Aβ assembly and held responsible to trigger the pathogenesis of Alzheimer’s disease (AD). Thus, Aβ oligomers are a prominent target in AD drug… read more here.

Keywords: disease vitro; preclinical pharmacokinetic; alzheimer disease; disease ... See more keywords