Assessing the relative potency of (S)- and (R)-warfarin with a new PK-PD model, in relation to VKORC1 genotypes
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DOI: 10.1007/s00228-017-2248-9
Abstract: PurposeThe purpose of this study is to develop a new pharmacokinetic-pharmacodynamic (PK-PD) model to characterise the contribution of (S)- and (R)-warfarin to the anticoagulant effect on patients in treatment with rac-warfarin.MethodsFifty-seven patients starting warfarin (W)… read more here.
Keywords: potency; assessing relative; effect; model ... See more keywords