Design, synthesis and biological evaluation of some novel quinazolinone derivatives as potent apoptotic inducers.
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DOI: 10.4155/fmc-2017-0284
Abstract: AIM Novel quinazolinone and triazinoquinazolinone derivatives were designed and synthesized as apoptotic inducers. METHODOLOGY/RESULTS Most of the synthesized compounds showed excellent antiproliferative activity against MCF-7 and HCT-116 cell lines, respectively. Compounds 7a, 8a, 8d, 14a… read more here.
Keywords: hct 116; potent apoptotic; novel quinazolinone; apoptotic inducers ... See more keywords