Highly Potent Cell-Permeable and Impermeable NanoLuc Luciferase Inhibitors.
Sign Up to like & getrecommendations! Published in 2017 at "ACS chemical biology"
DOI: 10.1021/acschembio.6b01129
Abstract: Novel engineered NanoLuc (Nluc) luciferase being smaller, brighter, and superior to traditional firefly (Fluc) or Renilla (Rluc) provides a great opportunity for the development of numerous biological, biomedical, clinical, and food and environmental safety applications.… read more here.
Keywords: highly potent; cell permeable; potent cell; nluc ... See more keywords
Circular RNA vaccine induces potent T cell responses
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2302191120
Abstract: Significance Circular RNAs (circRNAs) are a unique class of RNAs that are highly stable compared to linear mRNAs and can be engineered to provide durable protein expression. This study demonstrates that circRNA encoding antigenic protein… read more here.
Keywords: potent cell; cell responses; rna vaccine; vaccine induces ... See more keywords
Identification of B-Cell Epitopes for Eliciting Neutralizing Antibodies against the SARS-CoV-2 Spike Protein through Bioinformatics and Monoclonal Antibody Targeting
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23084341
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global public health crisis. Effective COVID-19 vaccines developed by Pfizer-BioNTech, Moderna, and Astra Zeneca have made significant impacts in controlling the COVID-19 burden, especially in… read more here.
Keywords: potent cell; neutralizing antibodies; identification; cell epitopes ... See more keywords