The effect of potent CYP2D6 inhibition on the pharmacokinetics and safety of deutetrabenazine in healthy volunteers.
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DOI: 10.1007/s00228-021-03202-0
Abstract: PURPOSE Deutetrabenazine is a deuterated form of tetrabenazine with a confirmed lower rate of CYP2D6 metabolism of the active metabolites, α- and β-HTBZ. In this study, we assessed the effect of paroxetine, a potent CYP2D6… read more here.
Keywords: safety deutetrabenazine; safety; potent cyp2d6; effect ... See more keywords