Discovery of Potent DYRK2 Inhibitors with High Selectivity, Great Solubility, and Excellent Safety Properties for the Treatment of Prostate Cancer.
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DOI: 10.1021/acs.jmedchem.3c00106
Abstract: Prostate cancer (PCa) is a common male cancer with high incidence and mortality, and hormonal therapy as the major treatment for PCa patients is troubled by the inevitable resistance that makes us identify novel targets… read more here.
Keywords: prostate cancer; safety properties; potent dyrk2; high selectivity ... See more keywords