A potent HNF4α agonist reveals that HNF4α controls genes important in inflammatory bowel disease and Paneth cells
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0266066
Abstract: HNF4α has been implicated in IBD through a number of genome-wide association studies. Recently, we developed potent HNF4α agonists, including N-trans caffeoyltyramine (NCT). NCT was identified by structural similarity to previously the previously identified but… read more here.
Keywords: paneth; high fat; paneth cells; potent hnf4 ... See more keywords