Development of Potent Immune Modulators Targeting Stimulator of Interferon Genes Receptor.
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DOI: 10.1021/acs.jmedchem.1c01795
Abstract: Stimulator of interferon genes (STING) is an endoplasmic reticulum-membrane protein that plays important roles in cancer immunotherapy by activating innate immune responses. We designed and synthesized STING modulators and characterized compounds 4a and 4c that… read more here.
Keywords: development potent; potent immune; stimulator interferon; interferon ... See more keywords