Structural Optimization and MD Simulation Study of Benzimidazole Derivatives as Potent Mutant FLT3 Kinase Inhibitors Targeting AML
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DOI: 10.1002/ardp.70002
Abstract: Acute myeloid leukemia (AML) is an aggressive hematological malignancy with poor survival rates in adults, posing a significant economic burden. FMSâlike tyrosine kinase 3 (FLT3) mutations are linked to poor prognosis in AML and resistance… read more here.
Keywords: potent mutant; mutant flt3; flt3; cell ... See more keywords