Development of Potent Nanosized Isatin-isonicotinohydrazide Hybrid for Management of Mycobacterium Tuberculosis.
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DOI: 10.1016/j.ijpharm.2021.121369
Abstract: Inspired by the antitubercular activity of isoniazid (INH) and 5-bromoisatin, isatin-INH hybrid (WF-208) has been synthesized as a potent agent against multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains of M. tuberculosis. In silico molecular docking… read more here.
Keywords: development potent; potent nanosized; tuberculosis; compound ... See more keywords