Discovery of novel thiophene derivatives as potent neuraminidase inhibitors.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2021.113762
Abstract: Neuraminidase (NA) is an important target for the treatment of influenza. In this study, a new lead NA inhibitor, 4 (ZINC01121127), was discovered by pharmacophore-based virtual screening and molecular dynamic (MD) simulation. Some novel NA… read more here.
Keywords: derivatives potent; thiophene derivatives; potent neuraminidase; thiophene ... See more keywords