Potential acetylcholinesterase inhibitors: molecular docking, molecular dynamics, and in silico prediction
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Modeling"
DOI: 10.1007/s00894-017-3228-9
Abstract: AbstractThis paper deals with molecular modeling of new therapeutic agents for treating the Alzheimer’s disease. The therapeutic line adopted for this study is the cholinergic hypothesis. To modulate positively the cholinergic function through the inhibition… read more here.
Keywords: acetylcholinesterase; docking molecular; acetylcholinesterase inhibitors; inhibitors molecular ... See more keywords
Synthesis and molecular dynamic simulation studies of novel N-(1-benzylpiperidin-4-yl) quinoline-4-carboxamides as potential acetylcholinesterase inhibitors
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2021.130919
Abstract: Abstract A new series of N-(1-benzylpiperidin-4-yl) quinoline-4-carboxamide derivatives was designed and synthesized as potential acetylcholinesterase inhibitors. The compounds were characterized by nuclear magnetic resonance, infrared and mass spectrometry. In the amidation reaction in addition of… read more here.
Keywords: potential acetylcholinesterase; acetylcholinesterase inhibitors; benzylpiperidin quinoline; synthesis molecular ... See more keywords
Phytochemicals of Avocado Residues as Potential Acetylcholinesterase Inhibitors, Antioxidants, and Neuroprotective Agents
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27061892
Abstract: Avocado (Persea americana) is a widely consumed fruit and a rich source of nutrients and phytochemicals. Its industrial processing generates peels and seeds which represent 30% of the fruit. Environmental issues related to these wastes… read more here.
Keywords: acetylcholinesterase inhibitors; phytochemicals avocado; residues potential; avocado residues ... See more keywords