8-Hydroxyquinolin-2(1H)-one analogues as potential β2-agonists: Design, synthesis and activity study.
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DOI: 10.1016/j.ejmech.2021.113697
Abstract: β2-Agonists that bind to plasmalemmal β2-adrenoceptors causing cAMP accumulation are widely used as bronchodilators in chronic respiratory diseases. Here, we designed and synthesized a group of 8-hydroxyquinolin-2(1H)-one analogues and studied their β2-agonistic activities with a… read more here.
Keywords: design synthesis; potential agonists; agonists design; hydroxyquinolin one ... See more keywords