Insights into the potential antidepressant mechanisms of cilostazol in chronically restraint rats: impact on the Nrf2 pathway
Sign Up to like & getrecommendations! Published in 2018 at "Behavioural Pharmacology"
DOI: 10.1097/fbp.0000000000000335
Abstract: Ample evidence has pointed to a close link between oxidative stress, mitochondrial dysfunction, and depression. Nuclear factor-erythroid 2-related factor-2 (Nrf2) is a master regulator of cellular redox homeostasis and affects mitochondrial function. Nrf2 holds promise… read more here.
Keywords: potential antidepressant; antidepressant mechanisms; nrf2 pathway; insights potential ... See more keywords
The potential antidepressant effect of antidiabetic agents: New insights from a pharmacovigilance study based on data from the reporting system databases FAERS and VigiBase
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1128387
Abstract: Background: Growing evidence supports a bidirectional association between diabetes and depression; promising but limited and conflicting data from human studies support the intriguing possibility that antidiabetic agents may be used to relieve effectively depressive symptoms… read more here.
Keywords: faers vigibase; reporting system; potential antidepressant; pharmacovigilance ... See more keywords