Butyrate‐Mediated Upregulation of Insulin Pathway Gene Expression Suggests Potential Antidiabetic Effects
Sign Up to like & getrecommendations! Published in 2025 at "Drug Development Research"
DOI: 10.1002/ddr.70203
Abstract: Type 2 diabetes (T2D) is a major cause of morbidity in developed countries and involves insulin resistance, a failure to correctly respond to insulin. Numerous studies in rodent T2D models suggested that the short‐chain fatty… read more here.
Keywords: antidiabetic effects; insulin; effects butyrate; expression ... See more keywords
Antioxidative potential of antidiabetic agents: A possible protective mechanism against vascular complications in diabetic patients
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27278
Abstract: Many vascular complications are related to exposure of tissues to elevated levels of glucose, a condition that promotes oxidative stress. The primary goal of antidiabetic medication is for normalization of blood glucose. However, antidiabetic medications… read more here.
Keywords: agents possible; possible protective; potential antidiabetic; vascular complications ... See more keywords
Exploring the Therapeutic Potential of Antidiabetic Drugs in Cardiac Arrhythmia Management: A Drug Target Mendelian Randomization Study
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Arrhythmia"
DOI: 10.1002/joa3.70241
Abstract: Cardiac arrhythmias pose a major health concern while the role of antidiabetic medications in cardiac arrhythmic risks is not fully understood. read more here.
Keywords: drugs cardiac; antidiabetic drugs; therapeutic potential; exploring therapeutic ... See more keywords
Synthesis and evaluation of novel peptidomimetics bearing p-aminobenzoic acid moiety as potential antidiabetic agents.
Sign Up to like & getrecommendations! Published in 2020 at "Future medicinal chemistry"
DOI: 10.4155/fmc-2018-0372
Abstract: Aim: Search for new class of potential antidiabetic agents. Methodology: A series of novel peptidomimetics bearing the p-aminobenzoic acid moiety (TM3-TM6) were designed and synthesized. For all synthetic target molecules, the peroxisome proliferator response element… read more here.
Keywords: potential antidiabetic; aminobenzoic acid; peptidomimetics bearing; novel peptidomimetics ... See more keywords