Nucleoside analogs as potential antiviral agents for dengue virus infections
Sign Up to like & getrecommendations! Published in 2017 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-017-1863-4
Abstract: Dengue virus is the causative agent of dengue fever and also the most prevalent mosquito borne viral pathogen. Up until now, treatments for dengue fever rely mainly on intensive supportive therapies. This study aimed to… read more here.
Keywords: dengue virus; analogs potential; potential antiviral; nucleoside analogs ... See more keywords
Potential antiviral properties of antiplatelet agents against SARS-CoV-2 infection: an in silico perspective
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-021-02558-5
Abstract: SARS-CoV-2 represents the causative agent of the current pandemic (COVID-19). The drug repurposing technique is used to search for possible drugs that can bind to SARS-CoV-2 proteins and inhibit viral replication. In this study, the… read more here.
Keywords: properties antiplatelet; potential antiviral; silico; sars cov ... See more keywords
Design, synthesis and biological evaluation of gentiopicroside derivatives as potential antiviral inhibitors.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.02.028
Abstract: Based on classical drug design theory, a novel series of gentiopicroside derivatives was designed and synthesized. All synthesized compounds were then biologically evaluated for their inhibition of influenza virus and anti-HCV activity in vitro. Some of… read more here.
Keywords: design synthesis; antiviral inhibitors; potential antiviral; synthesis biological ... See more keywords
Development of Azaindole-Based Frameworks as Potential Antiviral Agents and Their Future Perspectives
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.2c00444
Abstract: The azaindole (AI) framework continues to play a significant role in the design of new antiviral agents. Modulating the position and isosteric replacement of the nitrogen atom of AI analogs notably influences the intrinsic physicochemical… read more here.
Keywords: based frameworks; azaindole based; potential antiviral; antiviral agents ... See more keywords
The Potential Antiviral Effects of Selenium Nanoparticles and Coated Surfaces
Sign Up to like & getrecommendations! Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11121683
Abstract: Modern epidemics quickly spread across borders and continents with devastating effects on both human health and the world economy. This issue is made worse by the various ways that infections are spread, including through aerosol,… read more here.
Keywords: potential antiviral; coated surfaces; selenium; selenium nanoparticles ... See more keywords
Potential Antiviral Strategy Exploiting Dependence of SARS-CoV-2 Replication on Lysosome-Based Pathway
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23116188
Abstract: The recent novel coronavirus (SARS-CoV-2) disease (COVID-19) outbreak created a severe public health burden worldwide. Unfortunately, the SARS-CoV-2 variant is still spreading at an unprecedented speed in many countries and regions. There is still a… read more here.
Keywords: potential antiviral; replication; replication lysosome; cov replication ... See more keywords
Potential Antiviral Properties of Industrially Important Marine Algal Polysaccharides and Their Significance in Fighting a Future Viral Pandemic
Sign Up to like & getrecommendations! Published in 2021 at "Viruses"
DOI: 10.3390/v13091817
Abstract: Over the decades, the world has witnessed diverse virus associated pandemics. The significant inhibitory effects of marine sulfated polysaccharides against SARS-CoV-2 shows its therapeutic potential in future biomedical applications and drug development. Algal polysaccharides exhibited… read more here.
Keywords: industrially important; potential antiviral; algal polysaccharides; important marine ... See more keywords