Efforts to maximize the potential of CAR-T therapy for cancer, from T-bodies to CAR-immune cells
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Hematology"
DOI: 10.1007/s12185-021-03213-8
Abstract: The scientific concept of genetically endowing T cells with target-specific tumoricidal activity using antibody-mediated antigen recognition was first described by Dr. Eshhar around 1990 [1]. Such engineered T cells, which were originally called “T-bodies”, are… read more here.
Keywords: potential car; efforts maximize; car; maximize potential ... See more keywords
Empowering the Potential of CAR-T Cell Immunotherapies by Epigenetic Reprogramming
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15071935
Abstract: Simple Summary Epigenetic mechanisms are key players in many diseases, including cancer. Unlike genetic changes, epigenetic modifications are reversible without leaving a permanent mark on DNA. Epigenetic therapies, using epigenome-influencing techniques, aim to normalize DNA… read more here.
Keywords: cell; potential car; empowering potential; car ... See more keywords