Discovery of coumarin-derived imino sulfonates as a novel class of potential cardioprotective agents.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2019.111779
Abstract: The burst of reactive oxygen species (ROS) contributes to and exacerbates cardiac injury. Exogenous supplementation of antioxidants or upregulation of endogenous antioxidant defense genes should be the potential therapies for cardiovascular disease. Sixteen coumarin-derived imino… read more here.
Keywords: potential cardioprotective; imino sulfonates; derived imino; coumarin derived ... See more keywords
POTENTIAL CARDIOPROTECTIVE EFFECT OF GENIPIN VIA CYCLOOXIDASE 2 SUPPRESSION AND P53 SIGNAL PATHWAY ATTENUATION IN INDUCED MYOCARDIAL INFARCTION IN RATS
Sign Up to like & getrecommendations! Published in 2022 at "Shock"
DOI: 10.1097/shk.0000000000002001
Abstract: ABSTRACT Background and aims: Genipin, an iridoid derived from geniposide by β-glucosidase hydrolysis, has shown potential benefit in the treatment of heart function insufficiency despite its unclear therapeutic mechanism. This study aimed to investigate the… read more here.
Keywords: genipin; myocardial infarction; potential cardioprotective; p53 ... See more keywords