Evaluation of Clinical Drug Interaction Potential of Clofazimine Using Static and Dynamic Modeling Approaches
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DOI: 10.1124/dmd.117.077834
Abstract: The 2016 World Health Organization treatment recommendations for drug-resistant tuberculosis (DR-TB) positioned clofazimine as a core second-line drug. Being identified as a cytochrome P450 (P450) inhibitor in vitro, a P450-mediated drug interaction may be likely… read more here.
Keywords: drug interaction; interaction potential; drug; potential clofazimine ... See more keywords