What are the drugs having potential against COVID-19?
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DOI: 10.1007/s00044-020-02625-1
Abstract: A disease emerged in the city of Wuhan, Hubei Province, Central China in the last month of 2019. It was pneumonia caused by a newly emerged coronavirus called COVID-19, later. Coronaviruses are enveloped RNA viruses… read more here.
Keywords: covid; chemistry; potential covid; drugs potential ... See more keywords
Superspreading potential of COVID-19 outbreak seeded by Omicron variants of SARS-CoV-2 in Hong Kong
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DOI: 10.1093/jtm/taac049
Abstract: Abstract Using two early transmission chains in Hong Kong, the estimated R and k were 1.34 (95%CrI: 0.94-2.19) and 0.33 (95%CrI: 0.17-0.62) respectively, inferring 20.3% (95%CrI: 12.7%-29.6%) cases were responsible for 80% of the transmissions… read more here.
Keywords: hong kong; omicron; superspreading potential; covid outbreak ... See more keywords
4’-fluorouridine as a potential COVID-19 oral drug?: a review
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DOI: 10.12688/f1000research.109701.2
Abstract: The available antiviral drugs against coronavirus disease 2019 (COVID-19) are limited. Oral drugs that can be prescribed to non-hospitalized patients are required. The 4′-fluoruridine, a nucleoside analog similar to remdesivir, is one of the promising candidates… read more here.
Keywords: antiviral activity; covid oral; fluorouridine; fluorouridine potential ... See more keywords
Unexposed populations and potential COVID-19 hospitalisations and deaths in European countries as per data up to 21 November 2021
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DOI: 10.2807/1560-7917.es.2022.27.1.2101038
Abstract: We estimate the potential remaining COVID-19 hospitalisation and death burdens in 19 European countries by estimating the proportion of each country’s population that has acquired immunity to severe disease through infection or vaccination. Our results… read more here.
Keywords: hospitalisations deaths; unexposed populations; european countries; covid hospitalisations ... See more keywords
Renoprotective Effects of Luteolin: Therapeutic Potential for COVID-19-Associated Acute Kidney Injuries
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DOI: 10.3390/biom12111544
Abstract: Acute kidney injury (AKI) has been increasingly reported in critically-ill COVID-19 patients. Moreover, there was significant positive correlation between COVID-19 deaths and renal disorders in hospitalized COVID-19 patients with underlying comorbidities who required renal replacement… read more here.
Keywords: covid patients; therapeutic potential; acute kidney; covid ... See more keywords
Potential COVID-19 Therapies from Computational Repurposing of Drugs and Natural Products against the SARS-CoV-2 Helicase
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DOI: 10.3390/ijms23147704
Abstract: Repurposing of existing drugs is a rapid way to find potential new treatments for SARS-CoV-2. Here, we applied a virtual screening approach using Autodock Vina and molecular dynamic simulation in tandem to screen and calculate… read more here.
Keywords: covid therapies; top hits; cov helicase; potential covid ... See more keywords
Potential COVID-19 Drug Candidates Based on Diazinyl-Thiazol-Imine Moieties: Synthesis and Greener Pastures Biological Study
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DOI: 10.3390/molecules27020488
Abstract: A novel series of 1-aryl-N-[4-phenyl-5-(arylazo)thiazol-2-yl)methanimines has been synthesized via the condensation of 2-amino-4-phenyl-5-arylazothiazole with various aromatic aldehydes. The synthesized imines were characterized by spectroscopic techniques, namely 1H and 13C-NMR, FTIR, MS, and Elemental Analysis. A… read more here.
Keywords: covid drug; greener pastures; potential covid; drug candidates ... See more keywords
Influences on Attitudes Regarding Potential COVID-19 Vaccination in the United States
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DOI: 10.3390/vaccines8040582
Abstract: The COVID-19 pandemic continues to ravage the world, with the United States being highly affected. A vaccine provides the best hope for a permanent solution to controlling the pandemic. However, to be effective, a vaccine… read more here.
Keywords: potential covid; united states; vaccination united; vaccination ... See more keywords