Spatiotemporal Modulation of Action Potential Duration in Intact Hearts by Sub-Thresholds Optogenetics Stimulation
Sign Up to like & getrecommendations! Published in 2020 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2019.11.2731
Abstract: Cardiac optogenetics is an emerging research field combining photo-sensitive ion channels such as channelrhodopsin-2 (ChR2) expressed in cardiomyocytes with targeted illumination to enable precise spatio-temporal modulation of cardiac electrical function. During the last years, optical… read more here.
Keywords: action potential; potential duration; spatiotemporal modulation; modulation action ... See more keywords
Robust estimation of field potential duration in multi-electrode array signals.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmacological and toxicological methods"
DOI: 10.1016/j.vascn.2019.05.094
Abstract: Electrical signals measured by microelectrode arrays (MEAs) allow non-invasive long-term monitoring of cardiomyocyte cultures. However, variability of local responses between electrodes and noise makes difficult the accurate estimation of the field potential duration (FPD). False… read more here.
Keywords: field potential; estimation; potential duration; estimation field ... See more keywords
The effect of myocardial action potential duration on cardiac pumping efficacy: a computational study
Sign Up to like & getrecommendations! Published in 2018 at "BioMedical Engineering OnLine"
DOI: 10.1186/s12938-018-0508-2
Abstract: Background and aimsAlthough studies on the relation between arrhythmias and the action potential duration (APD) have been carried out, most of them are based only on electrophysiological factors of the heart and lack experiments that… read more here.
Keywords: potential duration; apd; study; action potential ... See more keywords